Results 91 to 100 of about 22,548 (354)

Phosphatidylinositol(4,5)bisphosphate and Phosphatidylinositol(4)phosphate in Plant Tissues [PDF]

Plant Physiology, 1989
Pea (Pisum sativum) leaf discs or swimming suspensions of Chlamydomonas eugametos were radiolabeled with [(3)H]myo-inositol or [(32)P]Pi and the lipids were extracted, deacylated, and their glycerol moieties removed. The resulting inositol trisphosphate and bisphosphate fractions were examined by periodate degradation, reduction and dephosphorylation ...
R F, Irvine, A J, Letcher, D J, Lander, B K, Drøbak, A P, Dawson, A, Musgrave   +5 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Identification of atypical ether-linked glycerophospholipid species in macrophages by mass spectrometry

Journal of Lipid Research, 2010
A large scale profiling and analysis of glycerophospholipid species in macrophages has facilitated the identification of several rare and atypical glycerophospholipid species.
Pavlina T. Ivanova, Stephen B. Milne, H. Alex Brown   +2 more
doaj   +1 more source

Plasma membrane lipid remodeling during cold acclimation is mediated by the ER-PM contact sites-localized synaptotagmins 1 and 3 [PDF]

, 2016
Cold acclimation is the capacity of certain plants to increase their freezing tolerance in response to a period of low non-freezing temperatures.
Botella-Mesa, Miguel Angel, Osorio-Algar, Sonia, Pérez-Sancho, Jessica, Rosado, Abel, Ruiz-Lopez, Noemi, Salinas, Julio, Schapire, Arnaldo, Vanneste, Steffen, Willtmitzer, Lothar   +8 more
core  

Untargeted UPLC-MS Profiling Pipeline to Expand Tissue Metabolome Coverage: Application to Cardiovascular Disease. [PDF]

, 2015
Metabolic profiling studies aim to achieve broad metabolome coverage in specific biological samples. However, wide metabolome coverage has proven difficult to achieve, mostly because of the diverse physicochemical properties of small molecules ...
Alun H. Davies, Beltran A., Cubbon S., Elaine Holmes, Eliasson M., Elizabeth J. Want, Fahy E., Geier F. M., Gika H. G., Gika H. G., Giorgis Isaac, Gray N., Hao Z., Idborg H., Ismail N. A., Ivanisevic J., Jeremy K. Nicholson, Kanehisa M., Masson P., Mirnezami R., Muzaffar A. Anwar, Naz S., Nicholson J. K., Panagiotis A. Vorkas, Plumb R. S., Saric J., Schmidt C., Smith C. A., Spagou K., Spagou K., Vorkas P. A., Waldram A., Want E. J., Wishart D. S.   +33 more
core   +5 more sources

Production and analysis of multiply charged negative ions by liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry [PDF]

, 2020
RATIONALE: Liquid AP-MALDI has been shown to enable the production of ESI-like multiply charged analyte ions with little sample consumption and long-lasting, robust ion yield for sensitive analysis by mass spectrometry. Previous reports have focused on
Brown, Jeffery M., Cramer, Rainer, Hale, Oliver J., Morris, Michael, Ryumin, Pavel   +4 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development [PDF]

, 2017
Chorioamnionitis is associated with adverse neurodevelopmental outcomes in preterm infants. Ureaplasma spp. are the microorganisms most frequently isolated from the amniotic fluid of women diagnosed with chorioamnionitis.
Barre, F.P.Y., Beeton, Michael L., Cillero-Pastor, B., Gussenhoven, R., Heeren, R.M.A., Jobe, A.H., Kallapur, S.G., Kemp, M.W., Kessels, L., Kramer, B.W., Ophelders, D.R.M.G., Payne, M.S., Rutten, B.P., Spiller, O.B., Stevens, B., Stocks, S.J., Wolfs, T.G.A.M.   +16 more
core   +4 more sources

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

The Anti-Inflammatory Effect of Algae-Derived Lipid Extracts on Lipopolysaccharide (LPS)-Stimulated Human THP-1 Macrophages [PDF]

, 2015
Algae contain a number of anti-inflammatory bioactive compounds such as omega-3 polyunsaturated fatty acids (n-3 PUFA) and chlorophyll a, hence as dietary ingredients, their extracts may be effective in chronic inflammation-linked metabolic diseases such
Bidigare, Bojlul Bahar, Calder, Catherine Stanton, Chew, Choy, Christie, Dagmar Stengel, Freddy Guihéneuf, Gerald Fitzgerald, Guillard, Henderson, Matthias Schmid, R. Ross, Robertson, Ruairi Robertson, Williams   +16 more
core   +2 more sources