Results 131 to 140 of about 72,943 (293)

Lipid droplet associated protein HILPDA promotes hypoxia-induced ferroptosis by driving LPCAT3-mediated polyunsaturated phospholipids enrichment. [PDF]

PLoS One
Song Z, Li W, Zeng J, Wang X, Wang D, Liao X.   +5 more
europepmc   +1 more source

Analysis of the Recovery of Immune Status in the Patients With Paroxysmal Nocturnal Hemoglobinuria After Treatment With C5 Complement Inhibitor

Journal of Clinical Laboratory Analysis, EarlyView.
We retrospectively evaluated the impact of C5 complement inhibition on immune cell profiles and recovery in 27 PNH patients; both CD4+ and CD8+ T cells exhibited partial recovery, while B cell counts increased but remained below normal levels. In contrast, Treg cells were significantly reduced in PNH patients and showed no notable change post‐treatment.
Hui Liu, Mengting Che, Liyan Li, Honglei Wang, Chaomeng Wang, Junshu Wu, Yingying Chen, Zhaoyun Liu, Lijuan Li, Rong Fu   +9 more
wiley   +1 more source

Quantitative lipidomic analysis of blood and milk in jennies with high and low milk fat content. [PDF]

Vet Anim Sci
Zhang LT, Zhang K, Yan QX, Deng L, Degen A, Liu LL, Zhou XL.   +6 more
europepmc   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen, Shu‐Yu Hu, Chao‐Min Cheng, Ching‐Ju Shen   +3 more
wiley   +1 more source

Lipidome profiles and sleep disorders: A Mendelian randomization analysis of insomnia, sleep terrors, sleep apnea, and circadian rhythm disturbances. [PDF]

Medicine (Baltimore)
Li J, Shi J, Chen Y, Guo Y.
europepmc   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Mendelian randomization analysis reveals no causal association between non-alcoholic fatty liver disease and hepatocellular carcinoma: implications for lipid metabolomics and shared pathophysiological mechanisms. [PDF]

Discov Oncol
Wei Y, Li J.
europepmc   +1 more source

Ether Phosphatidylserine from Soft Coral <i>Sclerophytum heterospiculatum</i> Reveals Antioxidant Activity and Modulates Lipid Composition in LPS-Activated Human Microglial HMC-3 Cells. [PDF]

Mar Drugs
Bizikashvili ET, Ponomarenko AI, Ermolenko EV, Manzhulo IV.   +3 more
europepmc   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models. [PDF]

Antioxidants (Basel)
Antonowski T, Osowski A, Wojtkiewicz J.
europepmc   +1 more source