Results 91 to 100 of about 133,958 (282)

Phosphatidylserine hide-and-seek [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
Every day, billions of new cells are produced in our bodies, and an equivalent number must die. Normally this occurs by apoptosis (1), during which the chromatin compacts against the nuclear envelope, followed rapidly by nuclear fragmentation and budding into multiple membrane-bound apoptotic bodies. This “dance of death” results from the activation of
openaire   +2 more sources

Distribution, dynamics and functional roles of phosphatidylserine within the cell

open access: yesCell Communication and Signaling, 2019
Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most abundant anionic phospholipid in the eukaryotic cell accounting for up to 10% of the total cellular lipid. Much of what is known about PtdSer is the role exofacial
J. Kay, G. Fairn
semanticscholar   +1 more source

Phosphatidylserine externalization, “necroptotic bodies” release, and phagocytosis during necroptosis

open access: yesPLoS Biology, 2017
Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain-like (MLKL) proteins. It is considered to be a form of regulated necrosis, and, by lacking the “find me”
S. Zargarian   +8 more
semanticscholar   +1 more source

Induction of Suicidal Erythrocyte Death by Nelfinavir

open access: yesToxins, 2015
The HIV protease inhibitor, nelfinavir, primarily used for the treatment of HIV infections, has later been shown to be effective in various infectious diseases including malaria. Nelfinavir may trigger mitochondria-independent cell death.
Rosi Bissinger   +2 more
doaj   +1 more source

2014 REU Poster: Quantifying Lipid Contents In Liposomes with Enveloped Plasmonic Nanoparticles [PDF]

open access: yes, 2014
Poster presentation at REU Summer's End Research Symposium, 2014, by REU participant Beatrix Seytono, Calhoun Community College - Bjoern Reinhard group, Amin Feizpour lab mentor.Phosphatidylserine(PS) and monosialotetrahexosylganglioside(GM1) are ...
Seytono, Beatrix
core   +1 more source

Mechanisms of apoptotic phosphatidylserine exposure [PDF]

open access: yesCell Research, 2013
It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C.
Guillermo, Mariño, Guido, Kroemer
openaire   +2 more sources

ANALYSIS OF PLASMA MEMBRANE INEGRITY BY USING OF FLUORESCEIN LABELED ANNEXIN V AND ITS RELATIONSHIP TO MOTILITY AND VIABILITY OF RAM SPERM AFTER CRYOPRESERVATION [PDF]

open access: yesJournal of Central European Agriculture, 2006
The present study was conducted to detect sperm apoptosis in fresh, capacitated and frozen ram semen and to determine its relationship with other seminal parameters as motility and viability.
Maria IVANOVA-KICHEVA   +4 more
doaj  

Stimulation of Erythrocyte Cell Membrane Scrambling by Mushroom Tyrosinase

open access: yesToxins, 2014
Background: Mushroom tyrosinase, a copper containing enzyme, modifies growth and survival of tumor cells. Mushroom tyrosinase may foster apoptosis, an effect in part due to interference with mitochondrial function.
Leonie Frauenfeld   +3 more
doaj   +1 more source

Aminoglycoside induces RIPOR2 translocation and phosphatidylserine externalization via distinct mechanisms

open access: yesFrontiers in Cellular Neuroscience
Aminoglycosides are widely used to treat severe infections. However, systemically administered AGs preferentially kill cochlear hair cells, resulting in irreversible hearing loss. Recently, we found that AGs induce a rapid translocation of RIPOR2 in hair
Jinan Li   +4 more
doaj   +1 more source

Induction of Suicidal Erythrocyte Death by Cantharidin

open access: yesToxins, 2015
The natural phosphoprotein phosphatase inhibitor cantharidin, primarily used for topical treatment of warts, has later been shown to trigger tumor cell apoptosis and is thus considered for the treatment of malignancy. Similar to apoptosis of tumor cells,
Kousi Alzoubi   +5 more
doaj   +1 more source

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