Detection of phosphatidylserine-positive exosomes for the diagnosis of early-stage malignancies
British Journal of Cancer, 2017 Background:There has been increasing interest in the detection of tumour exosomes in blood for cancer diagnostics. Most studies have focussed on miRNA and protein signatures that are surrogate markers for specific tumour types.
Raghava Sharma +3 more
semanticscholar +1 more source
Piperlongumine-Induced Phosphatidylserine Translocation in the Erythrocyte Membrane
Toxins, 2014 Background: Piperlongumine, a component of Piper longum fruit, is considered as a treatment for malignancy. It is effective by inducing apoptosis. Mechanisms involved in the apoptotic action of piperlongumine include oxidative stress and activation of ...
Rosi Bissinger +4 more
doaj +1 more source
The Feasibility of Imaging Myocardial Ischemic/Reperfusion Injury Using \u3csup\u3e99m\u3c/sup\u3eTc-labeled Duramycin in a Porcine Model [PDF]
, 2015 When pathologically externalized, phosphatidylethanolamine (PE) is a potential surrogate marker for detecting tissue injuries. 99mTc-labeled duramycin is a peptide-based imaging agent that binds PE with high affinity and specificity.
Audi, Said H. +10 more
core +1 more source
Curvature and Bending Constants for Phosphatidylserine-Containing Membranes [PDF]
, 2003 Nola Fuller +2 more
openalex +1 more source
Engineering Phosphatidylserine Containing Asymmetric Giant Unilamellar Vesicles
MembranesThe plasma membrane lipid distribution is asymmetric, with several anionic lipid species located in its inner leaflet. Among these, phosphatidylserine (PS) plays a crucial role in various important physiological functions.
Jake McDonough +5 more
doaj +1 more source
Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]
, 2016 B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core +1 more source
B1-cell-produced anti-phosphatidylserine antibodies contribute to lupus nephritis development via TLR-mediated Syk activation [PDF]
, 2023 Kongyang Ma +21 more
openalex +1 more source
Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?
Open BiologyCalmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for diverse lipid moieties, including those found on CaM-binding proteins. These facts, together with our observation
Federica Scollo +12 more
doaj +1 more source