Results 161 to 170 of about 9,975 (285)

Profiling Protein Citrullination in Extracellular Vesicles by Single‐Molecule Detection Using Direct Stochastic Optical Reconstruction Microscopy

Journal of Biophotonics, EarlyView.
This study identifies post‐translationally citrullinated/deiminated protein cargoes co‐localised to EV subtypes, using super resolution microscopy and dSTORM imaging. The findings expand current understanding of post‐translational modifications in EV‐mediated cellular communication.
Sarah R. Needham, Benjamin M. Davis, Pinar Uysal‐Onganer, Daniel J. Rolfe, Mariya Hristova, Igor Kraev, Jameel M. Inal, Sigrun Lange   +7 more
wiley   +1 more source

Metabolism of polyunsaturated fatty acids in human bone marrow derived mesenchymal stromal cells [PDF]

, 2017
The application of human bone marrow derived mesenchymal stromal cells (hBMSCs) for regenerative or immunomodulatory therapies, e.g. treatment of the graft-versus-host disease, requires in vitro expansion of the cells.
Tigistu-Sahle, Feven
core  

Prothrombin Contributes to the Assembly of the Factor Va-Factor Xa Complex at Phosphatidylserine-containing Phospholipid Membranes [PDF]

, 1995
Didier Billy, George M. Willems, H.C. Hemker, Theo Lindhout   +3 more
openalex   +1 more source

Phosphatidylserine controls synaptic targeting and membrane stability of ASIC1a [PDF]

, 2022
Di-Shi Liu, Xing-Lei Song, Ming‐Gang Liu, Jian‐Fei Lu, Yu Huang, Jaepyo Jeon, Guofen Ma, Yong Li, Lucas Pozzo‐Miller, Michael X. Zhu, Tian‐Le Xu   +10 more
openalex   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Peripheral versus Marrow Lipidomics in Patients with Severe Aplastic Anemia: Potential Indicators for Early Immunosuppressive Treatment Response

Lipids, EarlyView.
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun, Yilei Hong, Yaonan Hong, Chuanao Xin, Qi Liu, Huijin Hu, Yingying Shen, Ying Chen, Shan Liu, Yiping Shen, Yuhong Zhou, Dijiong Wu   +11 more
wiley   +1 more source

Strategies for enhancing the therapeutic targeting of phosphatidylserine in oncological disorders and viral infections

, 2015
Iona Shu-Yi Easthope
openalex   +2 more sources

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Phospholipid Interconversion and Transport Are Altered in Glaucoma. [PDF]

FASEB J
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Edwards G, Kaur R, Mueller A, Ziebarth N, Lee RK, Bhattacharya SK.   +5 more
europepmc   +2 more sources

Structural characterization of Escherichia coli phosphatidylserine decarboxylase.

, 1988
Q X Li, William Dowhan
openalex   +1 more source