Results 161 to 170 of about 10,007 (332)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Identification of a novel, Ca²⁺‐dependent phospholipase D with preference for phosphatidylserine and phosphatidylethanolamine in Saccharomyces cerevisiae [PDF]

, 1996
Johannes A. Mayr, Sepp D. Kohlwein, Fritz Paltauf   +2 more
openalex   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function [PDF]

, 2009
Simone M. Schoenwaelder, Yuping Yuan, Emma C. Josefsson, M. J. D. White, Yao Yu, Kylie D. Mason, Lorraine A. O’Reilly, Katya J. Henley, Akiko Ono, Sarah Hsiao, Abbey Willcox, Andrew W. Roberts, David C.S. Huang, Hatem H. Salem, Benjamin T. Kile, Shaun P. Jackson   +15 more
openalex   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Effect of Phosphatidylserine Content on the Partition Coefficients of Diazepam and Flurazepam between Phosphatidylcholine-Phosphatidylserine Bilayer of Small Unilamellar Vesicles and Water Studied by Second Derivative Spectrophotometry.

, 2002
Ahmed A. Omran, Keisuke Kitamura, Shigehiko Takegami, Tatsuya Kitade, Abdel-Aziz Y. El-Sayed, Mahmoud H. Mohamed, Mohamed Abdel‐Hakim   +6 more
openalex   +2 more sources

A Phosphatidylserine-binding Site in the Cytosolic Fragment of Clostridium sordellii Lethal Toxin Facilitates Glucosylation of Membrane-bound Rac and Is Required for Cytotoxicity [PDF]

, 2004
Bruno Mesmin, Karine Robbe-Sermesant, Blandine Geny, Frédéric Luton, Gérard Brandolin, Michel R. Popoff, Bruno Antonny   +6 more
openalex   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

Structural Determination of Lysosphingomyelin-509 and Discovery of Novel Class Lipids from Patients with Niemann–Pick Disease Type C [PDF]

, 2019
Niemann–Pick disease type C (NPC) is an autosomal recessive disorder caused by the mutation of cholesterol-transporting proteins. In addition, early treatment is important for good prognosis of this disease because of the progressive neurodegeneration ...
Abe, A, Eto, Y, Fujii, K, Higaki, K, Iwahori, A, Jinnoh, I, Maekawa, M, Mano, N, Mashima, R, Matsumoto, Y, Narita, A, Ohno, K, Okuyama, T, Ozeki, Y, Saigusa, D, Shimoda, K, T Clayton, P, Takahashi, H, Tomioka, Y, Yamaguchi, H, Yamauchi, S   +20 more
core  

Detection of Phosphatidylserine by Using Liquid Crystal Supported on the Gold-Deposited Waveform Surfaces with the Annexin V-Based Signal Enhancement

, 2022
Duong Song Thai Duong, Chang‐Hyun Jang
openalex   +1 more source