Fish Sperm Subpopulations Detection, Separation, and Application: Current State and Trends
Modern advances in sperm biology highlight the necessity of recognising intra‐ejaculate heterogeneity as a central concept for advancing both the fundamental understanding of fertilisation processes and the development of artificial reproduction techniques in fishes. ABSTRACT Sperm subpopulations represent a fundamental manifestation of intra‐ejaculate
Viktoriya Dzyuba +2 more
wiley +1 more source
Improved red blood cell storage quality of blood from donors carrying the hypermorphic PIMT I120 variant. [PDF]
Bevers S +25 more
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Enhancing IR‐MALDESI MSI Spatial Resolution Through Beam Constriction With a Ring‐Actuated Iris
ABSTRACT Rationale Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) mass spectrometry imaging (MSI) enables label‐free, spatially resolved molecular analysis of biological tissues under ambient conditions. While improving spatial resolution is important for mapping fine tissue structures, mid‐infrared (IR) lasers are ...
Sarah M. Ashbacher +6 more
wiley +1 more source
Uncovering the Secret of Mesenchymal Stromal Cells Secretome: From Extracellular Vesicle Cargo to Neuroprotection. [PDF]
Joseph M +4 more
europepmc +1 more source
Defective NLRC5 signaling in macrophages drives TAM phenotype and anti‐inflammatory responses via STAT3/ERK, leading to tumor‐permissive conditions and gastric lymphoid neogenesis during Helicobacter infection. ABSTRACT The innate immune protein NLRC5 plays a key role in cancer immune surveillance.
Shambel Araya Haile +7 more
wiley +1 more source
This study investigated the effects of clinically relevant concentrations of doxorubicin (Dox; 5 μM), commonly used in anticancer therapy, on adipose‐derived stem cells (ADSCs). Dox induced ADSC dysfunction, characterized by reduced mitochondrial activity, apoptosis, oxidative stress, premature senescence, cytoskeletal alterations, and cell cycle ...
Aleksandra Skubis‐Sikora +5 more
wiley +1 more source
Targeting Phosphatidylserine in Advanced Gastric and Gastroesophageal Junction Adenocarcinomas: A Phase 2 Trial of Bavituximab Plus Pembrolizumab with Biomarker-Correlated Outcomes. [PDF]
Ntellas P +8 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
How can membrane lipid constituency be manipulated to produce liposomes with desired functions? [PDF]
Issler T +3 more
europepmc +1 more source

