Results 191 to 200 of about 31,210 (332)

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

The FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira, Solon Andrades da Rosa, Luiza Cherobini Pereira, Laura Boose de Mendonça, Juliete Scholl, Fabrício Figueiró, Thais Cardoso Bitencourt, Davi Piovesan Echevarria, João Luiz Aldinucci Buzzo, Jessica Boschini D'Agostin, Danieli Rosane Dallemole, Carolina Oliveira, Fernanda Simas, Fernanda Saez‐Calazans, Débora Santos‐Sousa, Guido Lenz, Eduardo C. Filippi‐Chiela   +16 more
wiley   +1 more source

Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

The FEBS Journal, Volume 293, Issue 11, Page 3320-3341, June 2026.
Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini, Caterina Di Sano, Samuele Raccosta, Mauro Manno, Giovanna Barbieri   +4 more
wiley   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Quantitative lipidomic analysis of blood and milk in jennies with high and low milk fat content. [PDF]

Vet Anim Sci
Zhang LT, Zhang K, Yan QX, Deng L, Degen A, Liu LL, Zhou XL.   +6 more
europepmc   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Characteristics, clinical outcomes and molecular mechanisms associated with severe diastolic dysfunction in aortic stenosis. [PDF]

J Mol Cell Cardiol Plus
Panaou K, Venema CS, van Bergeijk KH, Hadjicharalambous D, Girerd N, Trenkwalder T, Joner M, van der Harst P, Tromp J, Voors AA, Wykrzykowska JJ.   +10 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Metabolic Adaptation during Cardiac Exercise Rehabilitation in Patients after a First Myocardial Infarction. [PDF]

J Proteome Res
Bossi E, Nobile M, Paoletti F, Ticini L, Serrao S, Giglio A, Parati G, Zaza A, Crotti L, Malfatto G, Paglia G.   +10 more
europepmc   +1 more source

Redundant Glycerol‐3‐Phosphate Acyltransferases Regulate Thermo‐Sensitive Genic Male Sterility in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Thermo‐sensitive genic male sterility (TGMS) lines play a pivotal role in two‐line hybrid rice breeding. However, the availability of elite TGMS germplasm remains limited, and the molecular mechanisms underlying fertility transition of TGMS lines are still poorly understood.
Siqi Cheng, Hai Zheng, Yunlu Tian, Chaolong Wang, Xiaowen Yu, Kun Dong, Jian Wang, Jiayu Lu, Keyi Chen, Xiaodong He, Kun Shao, Junwen Gao, Bowen Yao, Yang Hu, Zhenwei Xie, Ling He, Zhao Xie, Yuantao Zhu, Song Guo, Dekun Lei, Anqi Jian, Xufei Zhu, Hao Yu, Shihao Zhang, Minrui Chen, Yun Chen, Ling Jiang, Yulong Ren, Xiuping Guo, Shijia Liu, Xi Liu, Shanshan Zhu, Zhigang Zhao, Jianmin Wan   +33 more
wiley   +1 more source

Lipid Composition of Camel Milk and Cow Milk in Xinjiang Province of China Analyzed by Method of Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry (UPLC-Q-TOF-MS). [PDF]

Food Sci Anim Resour
Miao J, Wang J.
europepmc   +1 more source