Results 221 to 230 of about 9,975 (285)

Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

The FEBS Journal, EarlyView.
Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini, Caterina Di Sano, Samuele Raccosta, Mauro Manno, Giovanna Barbieri   +4 more
wiley   +1 more source

Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi. [PDF]

PLoS Pathog
Gwynne PJ, Bourgeois JS, Pandit A, Asara JM, Hu LT.   +4 more
europepmc   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

Molecular Microbiology, EarlyView.
Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick, Thirumalai R. Kannan   +1 more
wiley   +1 more source

Sickle cell and autoimmune disease: a double whammy. [PDF]

Haematologica
De Kreuk AM.
europepmc   +1 more source

Natural Variation in TaFAD8‐D Promoter Enhances Thermotolerance in Wheat Through Fatty Acid and Lipid Remodelling

Plant Biotechnology Journal, EarlyView.
ABSTRACT Heat stress (HS) has become an increasing threat to wheat productivity under global warming. However, the genetic loci for thermotolerance and the underlying molecular mechanisms remain largely unknown. In this study, genetic mapping identified a thermotolerance locus, QMpe.cau‐2D, encoding fatty acid desaturase 8 (FAD8), with the transposable
Hongjian Yu, Tianyu Lan, Weiwei Mao, Yongfa Wang, Xiaoyu Zhang, Mengsi Ma, Shuo Chen, Guang Chen, Qiang Li, Zhaorong Hu, Mingming Xin, Yingyin Yao, Weilong Guo, Zhongfu Ni, Qixin Sun, Huiru Peng   +15 more
wiley   +1 more source

Advancing Clinical and Pathophysiological Insights into Pancreatitis Using Lipidomics and Metabolomics. [PDF]

Metabolites
Ahmed F, Zhao X, Setchell KDR, Abu-El-Haija M.   +3 more
europepmc   +1 more source

SARS-CoV-2 spike fusion peptide trans interaction with phosphatidylserine lipid triggers membrane fusion for viral entry

Puspangana Singh, Purba Pahari, Srija Mukherjee, Sharmistha Karmakar, Markus Hoffmann, Taraknath Mandal, Dibyendu Kumar Das   +6 more
openalex   +1 more source

Endocytic Sorting and Recycling Require Membrane Phosphatidylserine Asymmetry Maintained by TAT-1/CHAT-1

, 2010
Baohui Chen, Yue Jiang, Sheng Zeng, Jiacong Yan, Xin Li, Yan Zhang, Wei Zou, Xiaochen Wang   +7 more
openalex   +2 more sources

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Comprehensive metabolomic/lipidomic characterization of patients with mitochondrial ATP synthase, short-chain acyl-CoA dehydrogenase and combined variant deficiencies. [PDF]

Heliyon
Dobešová D, Prídavok M, Brumarová R, Kvasnička A, Piskláková B, Ivanovová E, Brennerová K, Šaligová J, Potočňáková Ľ, Drobňaková S, Potočňáková J, Friedecký D.   +11 more
europepmc   +1 more source