Results 221 to 230 of about 9,580 (237)
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Cell, 1983
Recently we described a saturable, high-affinity binding site for vesicular stomatitis virus (VSV) on the surface of Vero cells that appears to mediate viral infectivity. To isolate this binding site, we have extracted Vero cells with the detergent, octyl-beta-D-glucopyranoside.
Ira Pastan +3 more
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Recently we described a saturable, high-affinity binding site for vesicular stomatitis virus (VSV) on the surface of Vero cells that appears to mediate viral infectivity. To isolate this binding site, we have extracted Vero cells with the detergent, octyl-beta-D-glucopyranoside.
Ira Pastan +3 more
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Separation procedures for phosphatidylserines
Journal of Chromatography B: Biomedical Sciences and Applications, 1998This paper reviews working procedures for the separation of phosphatidylserines (PS) in complex sample matrices. It begins with an introductory overview of important aspects of PS involvement in cellular lipid biochemistry. The main body of the review describes various procedures for the extraction, isolation, purification, and separation of the PS ...
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Flippase and scramblase for phosphatidylserine exposure
Current Opinion in Immunology, 2020In various biological processes, phosphatidylserine (PtdSer) that is normally sequestered to the inner leaflet of the plasma membrane (PM) is exposed to the cell surface. When platelets are activated, they expose PtdSer to activate the blood-clotting factors.
Takaharu Sakuragi +2 more
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Pharmacological Research, 1996
INTRODUCTION the first compound have been demonstrated on theCNS [7], and of the second on immune responses [8].The history of phosphatidylserine (PtdSer) beganmore than 50 years ago with its identification byFolch [1], as a constituent of the cephaline fraction, up BIOCHEMICAL ACTIONSto its clinical use for the treatment of the ‘ageingbrain’ [2]. This
Ileana Marconcini Pepeu +2 more
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INTRODUCTION the first compound have been demonstrated on theCNS [7], and of the second on immune responses [8].The history of phosphatidylserine (PtdSer) beganmore than 50 years ago with its identification byFolch [1], as a constituent of the cephaline fraction, up BIOCHEMICAL ACTIONSto its clinical use for the treatment of the ‘ageingbrain’ [2]. This
Ileana Marconcini Pepeu +2 more
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Modification of phosphatidylserine by hypochlorous acid
Chemistry and Physics of Lipids, 2009The binding of the heme enzyme myeloperoxidase to phosphatidylserine epitopes on the surface of non-vital polymorphonuclear leukocytes and other cells at inflammatory sites favours modifications of this phospholipid by myeloperoxidase products. As detected by MALDI-TOF mass spectrometry hypochlorous acid and the myeloperoxidase-hydrogen peroxide ...
Holger Spalteholz +4 more
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Interaction of vasopressin with phosphatidylserine bilayers
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1974Abstract Vasopressin causes a decrease in electrical resistance of phosphatidylserine bilayers. The magnitude of the decrease is a function of vasopressin and salt concentrations. The conducting channel is produced probably by aggregation of 4–5 molecules of the hormone.
Diana Bach, Israel R. Miller
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Studies on decarboxylation of phosphatidylserine
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1974Abstract 1. 1. The decarboxylation of phosphatidylserine to phosphatidylethanolamine has been studied in homogenate and subcellular fractions of mouse liver. 2. 2. Among various subcellular fractions, the mitochondrial fraction was found to possessed the highest activity of phosphatidylserine decarboxylase, and the supernatant possessed ...
Makoto Matsuda, T. Suda
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Exploiting Surface Phosphatidylserine
Science Signaling, 2008Many animals use the presence of the phospholipid phosphatidylserine (PS), on the outer leaflet of the plasma membrane, as a way to recognize and destroy apoptotic cells by phagocytic engulfment. In this issue, two papers illustrate the differential roles played by PS in normal cells and during virus infection (see the Perspective by Fairn
Stella M. Hurtley, L. Bryan Ray
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Pharmacological effects of phosphatidylserine liposomes
Nature, 1976PHARMACOLOGICAL studies on diacylphospholipids develop along two lines of investigation. In the first, preparations of liposomes are used as carriers of drugs either bound to the bilayer or entrapped inside the vesicles. Sonicated liposomes have been shown to be able to transport inhibitors or drugs to target sites in vitro1 and in vivo2. In the second,
E. Boarato +3 more
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Phase Changes of Phosphatidylserine in Monolayers
Lipid / Fett, 1990AbstractUsing a Langmuir film balance, experiments have been performed in order to study the interaction between Phosphatidylserine and mono and divalent ions. Compression isotherms of phosphatidylserine monolayers spread over subphases free of ions gave phase transitions highly dependent of the initial phospholipid quantity spread. The presence of 100
Reig Isart, Francisca +4 more
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