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Phosphatidylserine synthase from yeast
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997Whereas mammalian cells produce PS by a base exchange reaction from preexisting phospholipids, yeast cells synthesize PS from CDP-diacylglycerol and serine by the PS synthase reaction. Yeast PS synthase was purified to homogeneity and shown to have a molecular mass of 23 kDa. The activity is dependent on either Mg2+ or Mn2+ and Triton X-100. The enzyme
Satoshi Yamashita, Jun-ichi Nikawa
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Phosphatidylserine-Mediated Cellular Signaling
2013Phosphatidylserine (PS), a phospholipid with a negatively charged head group, is an important constituent of eukaryotic membranes. Rather than being a passive component of cellular membranes, PS plays an important role in a number of signaling pathways.
Jason G. Kay, Sergio Grinstein
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The interaction of hemoglobin with phosphatidylserine vesicles
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982The interaction of hemoglobin with phosphatidylserine vesicles at low ionic strength and pH conditions was studied. The fluorescence intensity of a lipid embedded probe was quenched by bound Hb but could not be reversed by an elevation of ionic strength and pH.
Yocheved Shviro +2 more
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Phosphatidylserine synthase from bacteria
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997This review summarizes the characteristics of two subclasses of phosphatidylserine synthases: subclass I of gram-negative bacteria and subclass II of gram-positive bacteria. Unlike other phospholipid biosynthetic enzymes, the phosphatidylserine synthases of gram-negative bacteria, the enzyme from Escherichia coli has been extensively examined and ...
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Phosphatidylserine Recruits Rac1
Science's STKE, 2006Rac1 is a member of the Rho family of guanosine triphosphatases (GTPases) and is involved in stimulating membrane ruffling and cell migration. Finkielstein et al . show, using liposome-binding assays, nuclear magnetic resonance assays, and lipid overlay assays, that purified Rac1, either prenylated or nonprenylated,
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Use of Phosphatidylserine in Alzheimer's Disease
Annals of the New York Academy of Sciences, 1991AMADUCCI, LUIGI +8 more
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