Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker
Chemistry – A European Journal, EarlyView.ABSTRACT In this study, we report the synthesis of an alkylene linker containing a terminal 2‐cyanoethyl protected selenium functionality for coupling at the 5'‐end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates.
Shivam Tikoo +2 more
wiley +1 more source
Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides. [PDF]
Angew Chem Int Ed EnglYu JK +4 more
europepmc +1 more source
Heteroatom‐Doped Graphdiynes and Their Applications in Photo‐/Electro‐Catalytic CO2 Conversion
Carbon Innovation, EarlyView.This review highlights the versatile role of doped graphdiyne (GDY) in boosting CO2 conversion, where metal and non‐metal doping simultaneously tune the electronic structure, create abundant active sites, and improve charge separation, light harvesting, and CO2 adsorption.
Fangzhou Yang +3 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
Gold(I) Phosphine/Phosphido‐Borohydride Complexes
European Journal of Inorganic Chemistry, EarlyView.Synthesis, structure, and electrochemical characteristics of a homologous series of gold(I) complexes featuring phosphine and phosphido–borohydride ligands. A homologous series of linear, mononuclear gold(I) phosphine/phosphido‐borohydride complexes, encompassing [Au(PR3)2]+ 1, [Au(PR3)(PR2BH3)] 2 and [Au(PR2BH3)2]– 3 (R = tBu, Ad), has been prepared ...
Matthew J. G. Sinclair +3 more
wiley +1 more source
Modular and Mild Assembly of Aryl Phosphines, Phosphine Oxides/Sulfides, Phosphinates, and Phosphonates Enabled by Photoinduced Divergent Construction of Aryl-P(III) and Aryl-P(V) Bonds. [PDF]
JACS AuSun H +8 more
europepmc +1 more source
Redox‐Active Bisphosphines Based on a W(II)‐Propargyl Complex Backbone
European Journal of Inorganic Chemistry, EarlyView.Three bisphosphine ligands based on tungsten(II) propargyl‐type alkyne complexes were synthesized and characterized. The methanolate derivative was used as a metalla‐ligand for the preparation of a binuclear bisphosphine‐κ2‐PdCl2 complex. In both cases, IR spectroelectrochemistry (IR‐SEC) measurements revealed a successive process following oxidation ...
Friederike M. Hamann +7 more
wiley +1 more source
Deoxygenative phosphonation of ketones by titanium. [PDF]
Chem SciWang Y, Yin K, Pang X, Shu XZ.
europepmc +1 more source
Masked Silylenes: Controlled Generation and Reactivity Under Thermal and Equilibrium Conditions
European Journal of Inorganic Chemistry, EarlyView.This Review provides an overview of masked silylenes as bench‐stable precursors that release silylenes (R2Si:) under thermal activation or reversible equilibria. Precursor preparation, generation pathways, and characteristic reactivity are summarized, including trapping chemistry, reversible interconversions, insertion‐type processes, and small ...
Kei Ota, Kanata Miyahara, Norio Nakata
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From Phosphinimines to Four‐Membered SiCPN Cations: Insights Into N–Si Bonding and Ring Strain
European Journal of Inorganic Chemistry, EarlyView.Sterically tuned N‐silyl phosphinimines enable four‐membered SiCPN cations. Hydride abstraction yields cyclic cations for Me and iPr substituents at silicon, while tBu gives a protonated intermediate. Multinuclear NMR spectroscopy, X‐ray crystallography, thermochemical density functional theory investigations, and natural bond orbital analyses reveal ...
Alexander Falk, Jonathan O. Bauer
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