Results 191 to 200 of about 161,329 (309)

Ensifentrine Added on to Dual Bronchodilator or Triple Therapy Demonstrates Clinically Meaningful Improvement in CAT Score in Symptomatic Patients with Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Siler TM, Rheault T, Reyner D, MacDonald-Berko M, Davidson J, Rickard K.   +5 more
europepmc   +1 more source

Engineering the bacterial nutrition strategy to control plant diseases

Journal of Integrative Plant Biology, EarlyView.
This commentary on Wang et al. (2025) and Phan et al. (2025) highlights previously undiscovered Xanthomonas pathways for nutrition acquisition, explains how Xanthomonas bacteria hijack host molecular machinery through their effector proteins, and discusses how these studies can be used to develop new disease resistance mechanisms.
Muhammad Arslan Mahmood, Shahid Mansoor, Muhammad Naveed Aslam   +2 more
wiley   +1 more source

Investigations of the voltage-gated Ca⁺⁺ channels and phosphodiesterase enzyme inhibitory-like potential explain the medicinal use of <i>Otostegia fruticosa</i> in diarrhea and hypermotile gut. [PDF]

Front Pharmacol
Rehman NU, Ansari MN, Alalaiwah NA, Alotibi EO, Karim A, Bahta T, Abujheisha KY, Noman M.   +7 more
europepmc   +1 more source

Aminoacyltransferase Stimulation of Protein Synthesis by Pig Adrenal Polysomes [PDF]

, 1967
Fries, M., Scriba, Peter Christian
core   +1 more source

Transcriptional adapter ADA2 regulates yield and end‐use quality through liquid–liquid phase separation in wheat

Journal of Integrative Plant Biology, EarlyView.
The transcriptional adapter ADA2 interacts with the histone acetyltransferase GCN5 to regulate starch and storage protein content in wheat grains through histone acetylation. ADA2 undergoes phase separation and is modulated by GCN5, affecting histone acetyltransferase activity and gene transcription.
Xiaobang Zhang, Ruijie Zhang, Yuhan Zhang, Tao Yang, Longfei Wu, Yuan Cao, Jun Xiao, Jigang Li, Xin Gao, Xinyou Cao, Jie Liu, Mingming Xin, Yuan Zong, Zhongfu Ni, Qixin Sun, Yingyin Yao   +15 more
wiley   +1 more source

Phosphodiesterase 8 regulation of excitation-contraction coupling as a target for cardiovascular disease: is it my turn now? [PDF]

Am J Physiol Heart Circ Physiol
Xu (许莹) Y, McConnell BK.
europepmc   +1 more source

Targeted Alkaline Phosphatase Therapy Enhances Alveolar Bone Healing in X‐Linked Hypophosphatemia in Mice

Journal of Periodontal Research, EarlyView.
Effects of exogenous tissue‐nonspecific alkaline phosphatase (TNAP) were analyzed in the Hyp mouse model of X‐linked hypophosphatemia (XLH). Maxillary first molars were extracted from wild‐type (WT) and Hyp mice at 6 weeks, and collagen gel ± TNAP was placed in sockets. In one group of Hyp mice, submucosal injections of TNAP or saline were delivered at
Aonjittra Phanrungsuwan, Bella Donnelly, José Luis Millán, Brian L. Foster   +3 more
wiley   +1 more source

Development and assessment of a peptide vaccine against ovarian cancer utilizing nanoliposomes loaded with P53, WT1, and CA125 epitopes. [PDF]

J Ovarian Res
Shariati F, Hashemi M, Peyvandi M, Jebali A, Entezari M.   +4 more
europepmc   +1 more source

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Nerandomilast in Autoimmune-Associated Interstitial Lung Diseases: Translating Evidence from Progressive Pulmonary Fibrosis Studies. [PDF]

J Clin Med
Perrotta F, Mariniello DF, Stella GM, Pagliaro R, Scialò F, Liakouli V, Forte G, Ciccia F, Bianco A, D'Agnano V.   +9 more
europepmc   +1 more source