Results 191 to 200 of about 90,061 (216)

Beyond cargo clearance: p62 coordinates cAMP signalling and autophagy to drive cell fate decisions in <i>Dictyostelium discoideum</i>. [PDF]

Autophagy Rep
Gautam S, Saran S.
europepmc   +1 more source

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 6, Page 475-486, September 2026.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

Sperm Retrieval in Non-Azoospermic Patients with Intact Ejaculation: A Narrative Review. [PDF]

Int J Fertil Steril
Amir Jannati N, Akhavizadegan H, Kalantari H, Sabbaghian M, Sadighi Gilani MA.   +4 more
europepmc   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao, Honghua Zhang, Jingyu Chen, Ziyu Qian, Ning Zhang, Yihua Zhang, Hui Ye, Jianbing Wu, Zhangjian Huang   +8 more
wiley   +1 more source

Phosphodiesterase 8 regulation of excitation-contraction coupling as a target for cardiovascular disease: is it my turn now? [PDF]

Am J Physiol Heart Circ Physiol
Xu (许莹) Y, McConnell BK.
europepmc   +1 more source

Understanding the Molecular Processes of Obesity and the Anti‐Obesity Properties of Bioactive Substances Found in Tea

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
ABSTRACT Obesity, a severe worldwide health concern, is characterized as an excessive deposit of fat in the human body. It has various ramifications that endanger human health and increase the financial expense. Obesity raises the risk of several illnesses, notably cardiovascular disease, NALFD, and diabetes, and has been associated with shorter ...
Sakhawat Riaz, Fan Wenni, Danish Kamal, Umber Mubeen, Abul Hassan, Arslan Ahmed, Munir Ahmed   +6 more
wiley   +1 more source

Synthesis and Pharmacological Evaluation of 6,7-Dihydro‑3<i>H</i>‑Oxazolo[3,4‑<i>a</i>]Pyrazine-5,8-Dione Compounds as Inhibitors of Phosphodiesterases 4 and 5. [PDF]

ACS Med Chem Lett
Helfstein DR, das Virgens MF, Rojas Moscoso JA, Zaminelli T, Toledo FT, Maia de Lima J, Medeiros LO, Marcello BA, Soares VM, Passos GR, de Padua SS, Wolf MEG, Carneiro LM, De Nucci G, Keppler AF, Mónica FZ.   +15 more
europepmc   +1 more source

Genetically Confirmed Localized Perianal Hailey-Hailey Disease Successfully Treated With Topical Difamilast: A Case Report. [PDF]

Cureus
Maekawa M, Yoshida K, Tanese K, Ohara F, Ishiko A.   +4 more
europepmc   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Ensifentrine Added on to Dual Bronchodilator or Triple Therapy Demonstrates Clinically Meaningful Improvement in CAT Score in Symptomatic Patients with Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Siler TM, Rheault T, Reyner D, MacDonald-Berko M, Davidson J, Rickard K.   +5 more
europepmc   +1 more source