Results 261 to 270 of about 225,115 (385)

Properties of 5'-phosphodiesterase from Aspergillus niger.

, 1977
Masao Fujimoto, Kazuo Fujiyama, Yuichiro Midorikawa, Tetsuro Fujishima, Akira Kuninaka, Hiroshi Yoshino   +5 more
openalex   +2 more sources

Detergent activation and solubilization of 2′:3′-cyclic nucleotide 3′-phosphodiesterase from isolated myelin and c6 cells [PDF]

, 1979
Neil R. Sims, Leonie B. Horvath, P. R. Carnegie   +2 more
openalex   +1 more source

NO-Induced Biofilm Dispersion in Pseudomonas aeruginosa Is Mediated by an MHYT Domain-Coupled Phosphodiesterase

Journal of Bacteriology, 2013
Yi Li, Sabrina Heine, Michael Entian, K. Sauer, N. Frankenberg‐Dinkel   +4 more
semanticscholar   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Hyperreactive Arterial Endothelial Cells in Atherogenesis and Cyclic AMP Phosphodiesterase Inhibitor in Prevention and Treatment of Atherosclerotic Disorders

, 1975
Takio Shimamoto
openalex   +2 more sources

Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF

Oncogene, 2013
S. Pullamsetti, G. Banat, Anja Schmall, Marten Szibor, Dawid Pomagruk, J. Hänze, Ewa Kołosionek, Jochen Wilhelm, Thomas Braun, F. Grimminger, Werner Seeger, Werner Seeger, Ralph T. Schermuly, Ralph T. Schermuly, R. Savai   +14 more
semanticscholar   +1 more source

New Topical and Systemic Treatments for Atopic Dermatitis

Clinical &Experimental Allergy, EarlyView.
This review summarises new topical and systemic treatments for atopic dermatitis, their relative effectiveness, and important safety data. ABSTRACT Atopic dermatitis is an inflammatory skin condition characterised by pruritus and a chronic relapsing–remitting course.
Sara Mirali, Aaron M. Drucker
wiley   +1 more source

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

, 1978
Randa E. Yee, Paul A. Liebman
openalex   +1 more source

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

Cell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You, Xiang‐yang Li, Hui Wang, Guo‐ping Zhao   +3 more
wiley   +1 more source

Genetically proxied inhibition of Phosphodiesterase-5 and cancer risks: A drug-target Mendelian randomization analysis. [PDF]

Sci Rep
Tang K, Li B, Wu X, Wang M.
europepmc   +1 more source