Results 271 to 280 of about 229,722 (383)

A bacterial nutrition strategy for plant disease control. [PDF]

Science
Wang S, Zhu L, Tian M, Wu W, Hu X, Li X, Wang J, Zhu Y, Xu J, Mou B, Yang J, Cui F, Li D, Cheng J, Liu Z, Wang MA, Qi L, Jin W, Luo ZQ, Zhou P, Lee YH, Staskawicz B, He SY, Sun W.   +23 more
europepmc   +1 more source

Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility

Circulation, 2007
Jayan Nagendran, S. Archer, Daniel Soliman, V. Gurtu, R. Moudgil, A. Haromy, Chantal N St Aubin, Linda Webster, I. Rebeyka, D. Ross, P. Light, J. Dyck, E. Michelakis   +12 more
semanticscholar   +1 more source

Targeted Alkaline Phosphatase Therapy Enhances Alveolar Bone Healing in X‐Linked Hypophosphatemia in Mice

Journal of Periodontal Research, EarlyView.
Effects of exogenous tissue‐nonspecific alkaline phosphatase (TNAP) were analyzed in the Hyp mouse model of X‐linked hypophosphatemia (XLH). Maxillary first molars were extracted from wild‐type (WT) and Hyp mice at 6 weeks, and collagen gel ± TNAP was placed in sockets. In one group of Hyp mice, submucosal injections of TNAP or saline were delivered at
Aonjittra Phanrungsuwan, Bella Donnelly, José Luis Millán, Brian L. Foster   +3 more
wiley   +1 more source

Identification of biomarkers of Shenhailong formula in benign prostatic hyperplasia treatment: An observation study using network pharmacology and Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Pan J, Yu M, Zhang L, Yin J, Liu J, Zhang S, Zhang P, Fan Q, Liu J, Li X.   +9 more
europepmc   +1 more source

Potentiation of antiaggregating activity of adenosine by a phosphodiesterase inhibitor, EG626 (oxagrelate), in human platelets in vitro.

, 1984
Hiroshi Azuma, Yoshimi Takashima, Masayuki Ishikawa, Toshiyuki Yamakado   +3 more
openalex   +1 more source

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, EarlyView.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

The Molecular Mechanism of PDE1 Regulation. [PDF]

Cells
Nielsen J, Langgård M, Tengberg JF, Kehler J.   +3 more
europepmc   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

Experimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings, Christopher P. Denton, Luigi Venetucci, Andrew W. Trafford   +3 more
wiley   +1 more source

Trends in Inhibitors, Structural Modifications, and Structure-Function Relationships of Phosphodiesterase 4: A Review. [PDF]

Biomolecules
Sánchez-Belmonte A, Matencio A, Conesa I, Vidal-Sánchez FJ, Trotta F, López-Nicolás JM.   +5 more
europepmc   +1 more source

Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

, 2009
Tong Zhou, Konstantin Akopiants, Susovan Mohapatra, Peck-Sun Lin, Kristoffer Valerie, Dale A. Ramsden, Susan P. Lees‐Miller, Lawrence F. Povirk   +7 more
openalex   +2 more sources