Results 281 to 290 of about 225,115 (385)

Kinetic mechanism of ENPP1 ATPase: Implications for aberrant calcification disorders and enzyme replacement therapy. [PDF]

J Biol Chem
Michalchik MM, Potchernikov T, Lester ER, Braddock DT, Cao W, De La Cruz EM.   +5 more
europepmc   +1 more source

Inhibitory effect of molecular moiety in papaverine structure on cyclic AMP-phosphodiesterase of smooth and cardiac muscles.

, 1978
Masayasu Kimura, Isami Waki, Ikuko Kimura   +2 more
openalex   +2 more sources

Evaluating the outcomes of pluripotent stem‐cell‐derived photoreceptor transplantation in retinal repair

The FEBS Journal, EarlyView.
Transplantation of stem cell‐derived photoreceptors in retinal repair. We summarize methods for differentiating stem cells and describe surgical techniques for transplanting photoreceptor precursors to restore visual function (A). The effectiveness of these techniques is assessed with behavioral (B) and in vitro assays (C) using mouse models that mimic
Darin Zerti, Birthe Dorgau, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako, Gerrit Hilgen   +5 more
wiley   +1 more source

ACTIONS OF PAPAVERINE ON INTESTINAL SMOOTH MUSCLE AND ITS INHIBITION OF CYCLIC AMP AND CYCLIC GMP PHOSPHODIESTERASES

, 1976
Masaaki Miyamoto, Issei Takayanagi, Hideo Ohkubo, Keijiro Takagi   +3 more
openalex   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

The FEBS Journal, EarlyView.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen, Jan Eric Maika, Raphael Josef Eberle, Nina Jahnke, Marcel Wiermer, Laura Hartmann, Rüdiger Simon, Georg Groth   +7 more
wiley   +1 more source

A light-activated GTPase in vertebrate photoreceptors: Regulation of light-activated cyclic GMP phosphodiesterase

, 1977
George L. Wheeler, Mark W. Bitensky
openalex   +1 more source

Sexual dysfunction care needs of gay, bisexual, and other men who have sex with men living with HIV in Montreal, Canada

HIV Medicine, EarlyView.
Abstract Objectives Sexual dysfunction (SD) is common among gay, bisexual and other men who have sex with men (GBM) with HIV, yet little is known about their views on SD care. We explored these views to inform patient‐centred SD care to improve care delivery and sexual health outcomes.
Francesco Avallone, Kim Engler, Ford Hickson, Joseph Cox, Eric Fortin, Sean Yaphe, Bertrand Lebouché   +6 more
wiley   +1 more source

Host-directed therapeutic targets in macrophages and their ligands against mycobacteria tuberculosis. [PDF]

Infect Immun
Li J, Wang Y, He L, Yang L, Tao T, Bai L, Luo Y.   +6 more
europepmc   +1 more source

Long‐Term Clinical Outcomes of Transurethral Resection of Hunner Lesions Combined With Bladder Hydrodistension for Patients With Interstitial Cystitis at a Tertiary Referral Center in Japan

International Journal of Urology, EarlyView.
ABSTRACT Objectives To report the long‐term clinical outcomes of transurethral resection of Hunner lesions with bladder hydrodistension in patients with Hunner lesion interstitial cystitis (HIC) at a tertiary referral center in Japan. Methods A retrospective chart review was conducted to evaluate the treatment outcomes of 104 patients with HIC who ...
Yoshiyuki Akiyama, Kenichi Hashimoto, Aya Niimi, Yukio Homma, Haruki Kume   +4 more
wiley   +1 more source