Results 181 to 190 of about 17,744 (296)

Evolutionary diversity of sphingolipid metabolism proteins in fungi. [PDF]

IMA Fungus
Płecha M, Sokołowska B, Barua D, Bartczak J, Sobczyk M, Koperska D, Kułakowska A, Komosa A, Muszewska A.   +8 more
europepmc   +1 more source

Caffeine and Headache: Exploring the Multifaceted Relationship

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Purpose To explore the multifaceted relationship between caffeine and headache disorders, focusing on its dual role as both an analgesic and a potential trigger and to summarize the mechanisms underlying its anti‐nociceptive effects. Method This narrative review synthesizes evidence from experimental, clinical, and epidemiological studies on ...
Mona Hussein, Amr Hassan, Salsabil Abo Al‐Azayem, Janu Thuraiaiyah, Henrik Winther Schytz, Anter Mothenna Abdullah Nasser, Rehab Magdy   +6 more
wiley   +1 more source

Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy. [PDF]

Invest Ophthalmol Vis Sci
Lessieur EM, Saadane A, Du Y, Kiser J, Oum A, Bollinger ZR, Lee CA, Tang J, Kern TS.   +8 more
europepmc   +1 more source

Double‐Stranded DNA Sensing cGAS‐STING Immune Signaling in a Rat Co‐Culture Model of the Blood–Brain Barrier

Cell Biochemistry and Function, Volume 44, Issue 6, June 2026.
ABSTRACT Double‐stranded DNA coming from, for example, viruses, bacteria, or apoptotic cells is recognized by the cGAS‐STING signaling pathway comprising the cyclic GMP‐AMP synthase (cGAS) and the stimulator of interferon genes (STING) receptors. The pathway induces type I interferon response and activates transcription of interferon‐stimulated genes ...
András Harazin, Line S. Reinert, Parvez Alam, Lea Hoy, Annemette Boe Marnow, Janni Nielsen, Anna Lorentzen, Daniel E. Otzen, Søren R. Paludan, Morten S. Nielsen   +9 more
wiley   +1 more source

Successful Revascularization of Chronic Total Occlusions in Patients With Chronic Thromboembolic Pulmonary Disease

Catheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2323-2334, June 1, 2026.
ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein, Peter J. Leary, Lauren N. Carlozzi, Samuel G. Rayner, Zachary L. Steinberg   +4 more
wiley   +1 more source

Covalent Binding of the Boronic Acid-Based Inhibitor GSK4394835A to Phosphodiesterase 3B, a Drug Target for Cardiovascular Disease. [PDF]

J Med Chem
Eaton SA, Christianson DW.
europepmc   +1 more source

Beyond Vasospasm: Dual Milrinone and Balloon Angioplasty in Refractory Delayed Cerebral Ischemia Post‐Subarachnoid Hemorrhage

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Cerebral vasospasm is a major complication of aneurysmal subarachnoid hemorrhage and a key contributor to delayed cerebral ischemia, which remains a leading cause of morbidity despite standard therapy with nimodipine and induced hypertension.
Paul Cardozo Gil, Willy Pozo Soto, Alejandro Sengoku Cadima, Pablo Flores, Jorge Botello Marin, Gustavo Averanga, Richy Hurtado Montaño, Nelson Montalvo Flores   +7 more
wiley   +1 more source

Redox Imbalance and NOS-Dependent Modulation of Superoxide in the Bladder Mucosa of Women With IC/BPS: A Preliminary Study. [PDF]

J Cell Mol Med
de Oliveira MG, Antunes E, Passos GR, Brito LGO, D'Ancona CAL, Monica FZ.   +5 more
europepmc   +1 more source

A Case of Chronic Thromboembolic Pulmonary Hypertension and Pregnancy, Managed With Pulmonary Endarterectomy: Clinical Challenges, Case Report, and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, potentially curable form of pulmonary hypertension, with limited data in pregnancy. We describe a 37‐year‐old woman with progressive dyspnea, back pain, and cough, whose evaluation revealed severe right ventricular enlargement, high pulmonary pressures, and extensive V/Q ...
Hassan Ahangar, Mohammad Ghasemi Palangi, Sepehr Gohari, Payman Yasami   +3 more
wiley   +1 more source

SIRT1: Protean roles at the nexus of health, disease, and therapeutics

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley   +1 more source