Results 241 to 250 of about 27,465 (289)

Advancing Obstructive Airway Disease Treatment: Dual PDE3/4 Inhibition as a Therapeutic Strategy. [PDF]

Cells
Sherpa RT, Koziol-White CJ, Panettieri RA.   +2 more
europepmc   +1 more source

Cyclic-FMN Is a Detectable, Putative Intermediate of FAD Metabolism. [PDF]

Biomolecules
Belfleur L, Kallio JP, Richter W, Gassman NR, Ziegler M, Migaud ME.   +5 more
europepmc   +1 more source

Colorectal Neoplasia Pathogenesis in Normal Appearing Colonic Mucosa -A Perspective With Focus on Eicosanoid Signaling Pathways. [PDF]

Cancer Med
Feddersen UR, Hendel SK, Berner-Hansen VH, Veedfald S, Berner-Hansen M, Bindslev N.   +5 more
europepmc   +1 more source

Development of a Genetically Encoded and Potent PDE6D Inhibitor. [PDF]

Chembiochem
Gómez-Mulas A, Schaffner-Reckinger E, Peeters H, Chippalkatti R, Dautbasic A, Smith MJ, Ismail S, Abankwa DK.   +7 more
europepmc   +1 more source

PDE11A Is a Phenotype Modulator of Primary Bilateral Macronodular Adrenal Hyperplasia: Results of a 334-Patient Series.

J Clin Endocrinol Metab
Vaduva P, Bouys L, Jouinot A, Espiard S, Chansavang A, Berthon A, Néou M, Vaczlavik A, Violon F, Charchar H, Kroiss M, Raverot G, Lasolle H, Guignat L, Libé R, Assié G, Tabarin A, Kamenicky P, Pasmant E, Fragoso M, Stratakis C, Ragazzon B, Bertherat J.   +22 more
europepmc   +1 more source

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Phosphodiesterase in Psoriasis

British Journal of Dermatology, 1969
SUMMARY. . Phosphodiesterase activity was determined by a fluorometric method using thymidine-5′-3–0-methoxy fluorescein phosphate as a substrate, in blood serum, finger-blood, normal skin, foreskin and psoriatic skin. Higher enzyme activity was found in psoriasis both in blood-serum and finger-blood in comparison with normal controls ...
F, Zaruba, M A, Karasek, E M, Farber
openaire   +2 more sources

Phosphodiesterase 4 inhibitors

Journal of the American Academy of Dermatology, 2018
Historically, drugs available for treating atopic dermatitis (AD) have been limited to topical corticosteroids and topical calcineurin inhibitors, with systemic immunosuppressants and phototherapy reserved for severe AD. Despite their efficacy and infrequent adverse events, phobia about the use of topical steroids and calcineurin inhibitors has limited
Rema, Zebda, Amy S, Paller
openaire   +2 more sources

Phosphodiesterase-5 Inhibitors

2013
Nitric oxide (NO) signaling plays a key role in modulating vascular tone and remodeling in the pulmonary circulation. The guanylate cyclase/cyclic guanylate monophosphate-signaling pathway primarily mediates nitric oxide signaling. This pathway is critical in normal regulation of the pulmonary vasculature, and is an important target for therapy in ...
Barbara A, Cockrill, Aaron B, Waxman
openaire   +2 more sources