Results 1 to 10 of about 45,633 (272)

Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis [PDF]

open access: yesOpen Biology, 2014
The inhibition of triosephosphate isomerase (TPI) in glycolysis by the pyruvate kinase (PK) substrate phosphoenolpyruvate (PEP) results in a newly discovered feedback loop that counters oxidative stress in cancer and actively respiring cells.
Nana-Maria Grüning   +2 more
exaly   +2 more sources

Enzyme I facilitates reverse flux from pyruvate to phosphoenolpyruvate in Escherichia coli

open access: yesNature Communications, 2017
Enzyme I, a component of the phosphoenolpyruvate-carbohydrate phosphotransferase system (PTS), converts phosphoenolpyruvate to pyruvate. Here, the authors show that Enzyme I facilitates also the reverse reaction during both gluconeogenic and glycolytic ...
Christopher P Long   +2 more
exaly   +2 more sources

Expression Profiles of Phosphoenolpyruvate Carboxylase and Phosphoenolpyruvate Carboxylase Kinase Genes in Phalaenopsis, Implications for Regulating the Performance of Crassulacean Acid Metabolism

open access: goldFrontiers in Plant Science, 2018
Phalaenopsis is one of the most important potted plants in the ornamental market of the world. Previous reports implied that crassulacean acid metabolism (CAM) orchids at their young seedling stages might perform C3 or weak CAM photosynthetic pathways ...
Chia-Yun Ping   +7 more
doaj   +2 more sources

Biocatalytic cascade for the synthesis of methylphosphonate from phosphoenolpyruvate [PDF]

open access: yesMicrobial Cell Factories
Background Methylphosphonate (Mpn), a building block for complex organophosphonate, is utilized in pharmaceuticals, agriculture, and chemical industries.
Qi Zhang   +5 more
doaj   +2 more sources

The Carbon Switch at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2 [PDF]

open access: goldFrontiers in Microbiology, 2019
Sulfolobus solfataricus P2 grows on different carbohydrates as well as alcohols, peptides and amino acids. Carbohydrates such as D-glucose or D-galactose are degraded via the modified, branched Entner–Doudoroff (ED) pathway whereas growth on peptides ...
Patrick Haferkamp   +6 more
doaj   +2 more sources

Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation

open access: yesNature Communications, 2017
Gluconeogenesis is downregulated in hepatocellular carcinoma. Here, the authors show that nuclear receptor Nur77 acts as a tumour suppressor sustaining gluconeogenesis by enhancing phosphoenolpyruvate carboxykinase (PEPCK1) stability via regulating its ...
Xue-li Bian, Hang-Zi Chen, Kun-Yi Chien
exaly   +2 more sources

Phosphoenolpyruvate [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2008
AbstractThe conversion of phosphoenolpyruvate (PEP) in glycolysis is coupled with the formation of ATP. This note discusses the origin of the energy required for ATP formation as arising from redistribution of energy in PEP when compared with its precursor, 2‐phosphoglycerate.
E J, Behrman, V, Gopalan
openaire   +3 more sources

sRNA scr5239 Involved in Feedback Loop Regulation of Streptomyces coelicolor Central Metabolism

open access: yesFrontiers in Microbiology, 2020
In contrast to transcriptional regulation, post-transcriptional regulation and the role of small non-coding RNAs (sRNAs) in streptomycetes are not well studied. Here, we focus on the highly conserved sRNA scr5239 in Streptomyces coelicolor.
Franziska Engel   +4 more
doaj   +1 more source

Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection

open access: yesIUCrJ, 2021
Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to ...
Jonathan A. Clinger   +4 more
doaj   +1 more source

Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Wild-type C. glutamicum ATCC 13032 is known to possess two enzymes with anaplerotic (C4-directed) carboxylation activity, namely phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx). On the other hand, C3-directed decarboxylation can be
Jannick Kappelmann   +8 more
doaj   +1 more source

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