Results 151 to 160 of about 86,461 (284)

Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut

open access: yesiMeta, Volume 4, Issue 3, June 2025.
The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen   +21 more
wiley   +1 more source

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 11, June 2025.
The graphical abstract illustrates the role of polysaccharides extracted from various natural raw materials (such as mushrooms, marine organisms, fruits, and vegetables) in modulating the gut microbiota. The process begins with the extraction and purification of polysaccharides, followed by assessing their structure‐activity relationship. Upon entering
Yigang Huang   +7 more
wiley   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

open access: yesModern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li   +3 more
wiley   +1 more source

Unlocking T‐Cell Plasticity in the Tumor Microenvironment: Implications for Cancer Progression and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
The tumor microenvironment (TME) shapes T‐cell plasticity, influencing cancer progression and therapeutic outcomes. Here, we summarize the phenotypic transitions and spatial distribution of T cells within the TME, highlighting their dual roles in therapeutic efficacy and resistance.
Xiao‐Hong Ding   +4 more
wiley   +1 more source

Phosphoenolpyruvate phosphotransferase system components positively regulate Klebsiella biofilm formation

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Klebsiella pneumoniae is one of the leading causes of device-related infections (DRIs), which are associated with attachment of bacteria to these devices to form a biofilm.
Yu-Tze Horng   +5 more
doaj  

Metformin use in women with polycystic ovary syndrome (PCOS): Opportunities, benefits, and clinical challenges

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S3, Page 31-47, June 2025.
Abstract Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is characterised by hormonal imbalances such as hyperandrogenism and anovulation, metabolic abnormalities including
Saeede Saadati   +5 more
wiley   +1 more source

Ligand induced cleavage and nuclear localization of the rice XA21 immune receptor [PDF]

open access: yes, 2012
The rice XA21 receptor confers immunity to the Gram-negative bacterial pathogen, _Xanthomonas oryzae_ pv. _oryzae_ (_Xoo_) upon recognition of the conserved microbial signature AxY^S^22.
Chang-Jin Park, Pamela C. Ronald
core   +1 more source

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