The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen+21 more
wiley +1 more source
Initial Characterization of Hexose and Hexitol Phosphoenolpyruvate-Dependent Phosphotransferases of Staphylococcus aureus [PDF]
Stanley Friedman, John B. Hays
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Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health
The graphical abstract illustrates the role of polysaccharides extracted from various natural raw materials (such as mushrooms, marine organisms, fruits, and vegetables) in modulating the gut microbiota. The process begins with the extraction and purification of polysaccharides, followed by assessing their structure‐activity relationship. Upon entering
Yigang Huang+7 more
wiley +1 more source
The maximum activities of hexokinase, phosphorylase, phosphofructokinase, glycerol phosphate dehydrogenases, lactate dehydrogenase, octopine dehydrogenase, phosphoenolpyruvate carboxykinase, nucleoside diphosphatekinase, glutamate-oxaloacetate transaminase and arginine kinase in relation to carbohydrate utilization in muscles from marine invertebrates [PDF]
Victor A. Zammit, E. A. Newsholme
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Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li+3 more
wiley +1 more source
The tumor microenvironment (TME) shapes T‐cell plasticity, influencing cancer progression and therapeutic outcomes. Here, we summarize the phenotypic transitions and spatial distribution of T cells within the TME, highlighting their dual roles in therapeutic efficacy and resistance.
Xiao‐Hong Ding+4 more
wiley +1 more source
Background/Purpose: Klebsiella pneumoniae is one of the leading causes of device-related infections (DRIs), which are associated with attachment of bacteria to these devices to form a biofilm.
Yu-Tze Horng+5 more
doaj
Pyruvate Carboxylase and Phosphoenolpyruvate Carboxykinase Activity in Leukocytes and Fibroblasts from a Patient with Pyruvate Carboxylase Deficiency [PDF]
Beth M Atkin+2 more
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Abstract Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is characterised by hormonal imbalances such as hyperandrogenism and anovulation, metabolic abnormalities including
Saeede Saadati+5 more
wiley +1 more source
Ligand induced cleavage and nuclear localization of the rice XA21 immune receptor [PDF]
The rice XA21 receptor confers immunity to the Gram-negative bacterial pathogen, _Xanthomonas oryzae_ pv. _oryzae_ (_Xoo_) upon recognition of the conserved microbial signature AxY^S^22.
Chang-Jin Park, Pamela C. Ronald
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