Results 11 to 20 of about 45,633 (272)

Ixodes scapularis Tick Cells Control Anaplasma phagocytophilum Infection by Increasing the Synthesis of Phosphoenolpyruvate from Tyrosine

Frontiers in Cellular and Infection Microbiology, 2017
The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of life-threatening diseases in humans and animals. A. phagocytophilum is an emerging tick-borne pathogen in the United States, Europe, Africa and Asia, with ...
Alejandro Cabezas-Cruz, Alejandro Cabezas-Cruz, Alejandro Cabezas-Cruz, Pedro J. Espinosa, Dasiel A. Obregón, Pilar Alberdi, José de la Fuente, José de la Fuente   +7 more
doaj   +1 more source

The Xylulose 5-Phosphate/Phosphate Translocator Supports Triose Phosphate, but Not Phosphoenolpyruvate Transport Across the Inner Envelope Membrane of Plastids in Arabidopsis thaliana Mutant Plants

Frontiers in Plant Science, 2018
The xylulose 5-phosphate/phosphate translocator (PTs) (XPT) represents a link between the plastidial and extraplastidial branches of the oxidative pentose phosphate pathway. Its role is to retrieve pentose phosphates from the extraplastidial space and to
Elke J. A. Hilgers, Pia Staehr, Pia Staehr, Ulf-Ingo Flügge, Rainer E. Häusler   +4 more
doaj   +1 more source

Production of succinate by engineered strains of Synechocystis PCC 6803 overexpressing phosphoenolpyruvate carboxylase and a glyoxylate shunt

Microbial Cell Factories, 2021
Background Cyanobacteria are promising hosts for the production of various industrially important compounds such as succinate. This study focuses on introduction of the glyoxylate shunt, which is naturally present in only a few cyanobacteria, into ...
Claudia Durall, Kateryna Kukil, Jeffrey A. Hawkes, Alessia Albergati, Peter Lindblad, Pia Lindberg   +5 more
doaj   +1 more source

An in vitro Coupled Assay for PEPC with Control of Bicarbonate Concentration

Bio-Protocol, 2021
Phosphoenolpyruvate carboxylase (PEPC) catalyzes a critical step in carbon metabolism in plants and bacteria, the irreversible reaction between bicarbonate and phosphoenolpyruvate to produce the C4 compound oxaloacetate.
Nicholas Moody, Chatawal Phansopal, James Reid   +2 more
doaj   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Regulation at the Phosphoenolpyruvate Branchpoint in Azotobacter vinelandii : Phosphoenolpyruvate Carboxylase [PDF]

Journal of Bacteriology, 1971
Phosphoenolpyruvate carboxylase (EC 4.1.1.31) from Azotobacter vinelandii , like the corresponding enzyme from other organisms, is activated by acetyl coenzyme A and inhibited by l -aspartate. Both modifiers affect primarily the affinity of the enzyme for phosphoenolpyruvate.
C L, Liao, D E, Atkinson
openaire   +2 more sources

Cloning and expression of phosphoenolpyruvate carboxykinase from Escherichia coli

Journal of Hebei University of Science and Technology, 2019
In order to better study the structure and function of phosphoenolpyruvate carboxylase, the phosphoenolpyruvate carboxylase gene is cloned and expressed by PCR (polymerase chain reaction), double enzyme digestion and cell transformation. The results show
Xiaoliang HE, Zhu2 LI, Liqiang2 LIANG, Wanli MENG, Lantian MIAO, Yaozu SUN, Hongguang2 CAI   +6 more
doaj   +1 more source

Peculiarities of the relationship between the terminal site of glycolysis and the initial segment of gluconeogenesis in the myocardium and skeletal muscles of animals irradiated at different doses

Journal of Education, Health and Sport, 2023
Existing types of muscles differ not only structurally, but also metabolically (direction of energy exchange, choice of biosubstrates, dependence on the action of mediators, hormones, etc.).
G. Stepanov, R. Vastyanov, A. Kostina, E. Mokriienko   +3 more
doaj   +1 more source

Stereoselective Interactions of Phosphoenolpyruvate Analogues with Phosphoenolpyruvate-utilizing Enzymes

Journal of Biological Chemistry, 1970
Abstract The optically pure d and l isomers of 2-phospholactate were synthesized by phosphorylation of the appropriate lactic acids. The interactions of these analogues and of phosphoglycolate with several enzymes that catalyze reactions of phosphoenolpyruvate were examined by kinetics and by direct binding studies measuring the longitudinal relaxation
T, Nowak, A S, Mildvan
openaire   +2 more sources

Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor

Proceedings, 2019
Phosphoenolpyruvate carboxykinase (PEPCK) is a key enzyme in gluconeogenesis, catalyzingthe decarboxylation of oxaloacetate to phosphoenolpyruvate. [...]
Sergio Rodríguez-Arévalo, Sònia Abás, Marc Aragó, Juan Moreno-Felici, Petra Hyroššová, Jose Carlos Perales, Carles Galdeano, Tiziana Ginex, Francisco Javier Luque, Carmen Escolano   +9 more
doaj   +1 more source