Combined transcriptomic-(1)H NMR metabonomic study reveals yhat monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes [PDF]
Adipose tissue is a major storage site for lipophilic environmental contaminants. The environmental metabolic disruptor hypothesis postulates that some pollutants can promote obesity or metabolic disorders by activating nuclear receptors involved in the ...
Beale E. G.+59 more
core +2 more sources
The haloarchaeon Haloferax volcanii grows on acetate as sole carbon and energy source. The genes and proteins involved in uptake and activation of acetate and in gluconeogenesis were identified and analyzed by characterization of enzymes and by growth ...
Tom Kuprat+3 more
doaj +1 more source
The CreC regulator of Escherichia coli, a new target for metabolic manipulations [PDF]
The CreBC (carbon source-responsive) two-component regulation system of Escherichia coli affects a number of functions, including intermediary carbon catabolism.
Cabrera Gomez, José Gregorio+3 more
core +1 more source
A recent study demonstrated that cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and NADP-malic enzyme (NADP-ME) have an important role in malate metabolism during fruit ripening (Osorio et al., 2013). PEPCK catalyze the ATP-dependent decarboxylation
Sonia Osorio+7 more
doaj +1 more source
Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin. [PDF]
Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis.
Chen, Tzu-Chieh+6 more
core +1 more source
Premise of the study: A novel branched DNA detection technology, RNAscope in situ hybridization (ISH), originally developed for use on human clinical and animal tissues, was adapted for use in plant tissue in an attempt to overcome some of the ...
Andrew J. Bowling+2 more
doaj +1 more source
Highlight This work documents the remarkable versatility and complexity of in vivo post-translational modifications (monoubiquitination and phosphorylation) of different plant-type phosphoenolpyruvate carboxylase (PEPC) isoenzymes during the life cycle ...
Isabel Ruíz-Ballesta+6 more
semanticscholar +1 more source
Anion channel sensitivity to cytosolic organic acids implicates a central role for oxaloacetate in integrating ion flux with metabolism in stomatal guard cells [PDF]
Stomatal guard cells play a key role in gas exchange for photosynthesis and in minimizing transpirational water loss from plants by opening and closing the stomatal pore.
Asai+56 more
core +4 more sources
Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
Blum, Werner F.+4 more
core +1 more source
Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem [PDF]
Subcellular compartmentation of plant biosynthetic pathways in the mitochondria and plastids requires coordinated regulation of nuclear encoded genes, and the role of these genes has been largely ignored by wood researchers. In this study, we constructed
Fierro Gutierrez, Ana Carolina Elisa+4 more
core +2 more sources