Results 91 to 100 of about 26,859 (247)

Cytosolic phosphoenolpyruvate carboxykinase deficiency : Expanding the clinical phenotype and novel laboratory findings [PDF]

, 2022
Cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) deficiency due to the homozygous PCK1 variant has recently been associated with childhood-onset hypoglycemia with a recognizable pattern of abnormal urine organic acids. In this study, 21 children and
Arkkola, Tuula, Haanpää, Maria K., Kaunisto, Kari, Keski-Filppula, Riikka, Latva, Katariina, Miettinen, Päivi J., Myllynen, Päivi, Nagy, Irina I., Nuutinen, Matti, Ojaniemi, Marja, Rahikkala, Elisa, Sidoroff, Virpi, Uusimaa, Johanna, Valmari, Pekka, Vieira, Päivi, Väisänen, Marja-Leena   +15 more
core   +1 more source

Guard cell‐specific glycine decarboxylase manipulation affects Arabidopsis photosynthesis, growth and stomatal behavior

New Phytologist, EarlyView.
Summary Photorespiration is a mandatory metabolic repair shunt of carbon fixation by the Calvin–Benson cycle in oxygenic phototrophs. Its extent depends mainly on the CO2 : O2 ratio in chloroplasts, which is regulated via stomatal movements. Despite a comprehensive understanding of the role of photorespiration in mesophyll cells, its role in guard ...
Hu Sun, Nils Schmidt, Tracy Lawson, Martin Hagemann, Stefan Timm   +4 more
wiley   +1 more source

Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets. [PDF]

PLoS ONE, 2014
In this study, gestational sows were fed control or betaine-supplemented diets (3 g/kg) throughout the pregnancy, and the newborn piglets were used to elucidate whether maternal dietary betaine affected offspring hepatic gluconeogenic genes through ...
Demin Cai, Yimin Jia, Haogang Song, Shiyan Sui, Jingyu Lu, Zheng Jiang, Ruqian Zhao   +6 more
doaj   +1 more source

Hypoxic pregnancy promotes fibrosis and increases stress metabolites in the ovine fetal liver

The Journal of Physiology, EarlyView.
Abstract Figure Legend: During hypoxic pregnancy, late gestation fetuses had increased periportal hepatic collagen deposition, an indicator of hepatic injury, with a unique profile of stress metabolites and adaptations in central carbon metabolism.
Molly M. McGuckin, Dong Wang, Jasmine Ortiz, Evgenia Dobrinskikh, Wen Tong, Kimberley J. Botting‐Lawford, Youguo Niu, Dino A. Giussani, Stephanie R. Wesolowski   +8 more
wiley   +1 more source

Untersuchungen zur Rolle der Phosphoenolpyruvat-Carboxykinase und des NADP+-Malat-Enzyms in der filamentösen Phaeophycee Ectocarpus siliculosus [PDF]

, 2003
In der filamentösen Braunalge Ectocarpus siliculosus liegen die Enzyme Phosphoenolpyruvat-Carboxykinase (PEPCK) und das NADP+-Malat-Enzym in hohen Aktivitäten vor. Die Beteiligung beider Enzyme an einem für die Alge vorgeschlagenen C4/CAM-
Busch, Sylvia, Galland, Paul (Prof. Dr.)
core   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

Modern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li, YiNing Zheng, HuiJun Geng, Lu Deng   +3 more
wiley   +1 more source

Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential

Frontiers in Pharmacology, 2020
BackgroundCarveol is a natural drug product present in the essential oils of orange peel, dill, and caraway seeds. The seed oil of Carum Carvi has been reported to be antioxidant, anti-inflammatory, anti-hyperlipidemic, antidiabetic, and hepatoprotective.
Muhammad Shabir Ahmed, Arif-ullah Khan, Lina Tariq Al Kury, Fawad Ali Shah   +3 more
doaj   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, Volume 15, Issue 5, Page 738-753, May 2025.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Transcriptomic response in Acropora muricata under acute temperature stress follows preconditioned seasonal temperature fluctuations

BMC Research Notes, 2018
Objective Global climate change has resulted in the decline of health and condition of various coral reefs worldwide. Here, we describe expression profiles of Acropora muricata collected during opposing seasons in Otsuki, Kochi, Japan to define the ...
Sonny T. M. Lee, Shashank Keshavmurthy, Silvia Fontana, Mezaki Takuma, Wen-Hua Chou, Chaolun Allen Chen   +5 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources