Results 81 to 90 of about 41,991 (249)

Correction: O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α. [PDF]

open access: yesPLoS ONE, 2017
[This corrects the article DOI: 10.1371/journal.pone.0179988.].
PLOS ONE Staff
doaj   +1 more source

Structural Insights into the Mechanism of Phosphoenolpyruvate Carboxykinase Catalysis [PDF]

open access: yesJournal of Biological Chemistry, 2009
Mammalian PEPCK2 catalyzes the reversible formation of PEP from OAA and GTP (or ITP) in a divalent cation-dependent reaction (Scheme 1), as was elegantly discussed in the first minireview of this series on PEPCK (1). SCHEME 1. PEPCK-catalyzed interconversion of OAA and PEP.
Gerald M, Carlson, Todd, Holyoak
openaire   +2 more sources

CO2 Fertilisation of Growth in Wild C4 Grasses may be Amplified by Upregulated Photosynthesis

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Rising atmospheric CO2 is expected to have limited direct effects on C4 photosynthesis because the carbon‐concentrating mechanism maintains near‐saturating CO2 at Rubisco. Consequently, growth responses of C4 plants to elevated CO2 (eCO2) are generally attributed to indirect improvements in plant water relations.
Edith J. Singini   +3 more
wiley   +1 more source

Inhibition of ERN1 suppresses the expression of phosphoenolpyruvate carboxykinase 2 in U87MG glioblastoma cells and increases its sensitivity to glucose and glutamine deprivation

open access: yesEndocrine Regulations
Objective. Phosphoenolpyruvate carboxykinase (PCK) catalyzes the conversion of oxaloacetate to phosphoenolpyruvate and regulates pyruvate metabolism and gluconeogenesis in response to glucocorticoid and insulin stimuli.
Viletska Yuliia M.   +6 more
doaj   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach   +5 more
wiley   +1 more source

Extending the Farquhar–von Caemmerer–Berry photosynthesis model to account for various photorespiratory bypasses

open access: yesNew Phytologist, Volume 252, Issue 3, Page 1327-1342, November 2026.
We extend a widely used C3‐photosynthesis model to account for various photorespiratory bypasses, thereby, providing a useful resource and framework that enforces future novel bypass work and scrutinize if the results go counter to theory. Our model analyses show that of the 17 published bypass pathways, full‐decarboxylating bypasses (that have been ...
Xinyou Yin   +3 more
wiley   +1 more source

Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP)*

open access: yesJournal of Biological Chemistry, 2013
Background: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-activated aryl hydrocarbon receptor (AHR) decreases gluconeogenesis by suppressing phosphoenolpyruvate carboxykinase (PEPCK) transcription via TCDD-inducible poly(ADP-ribose)-polymerase (TiPARP ...
Silvia Diani-Moore   +3 more
semanticscholar   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2713-2728, October 2026.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco   +8 more
wiley   +1 more source

Effects of Maternal Nutrient Restriction, IUGR, and Glucocorticoid Exposure on Phosphoenolpyruvate Carboxykinase-1 Expression in Fetal Baboon Hepatocytes In Vitro

open access: yesJournal of medical primatology, 2013
The objective of this study was to develop a cell culture system for fetal baboon hepatocytes and to test the hypotheses that (i) expression of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase‐1 (PEPCK‐1) is upregulated in hepatocytes isolated ...
Cun Li   +6 more
semanticscholar   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

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