Results 131 to 140 of about 43,737 (252)

Insufficient or Excessive Niacin Intake Induced Glucose and Lipid Metabolic Disorders and Impaired Liver Health in Nile Tilapia

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Niacin (vitamin B3) is involved in the metabolic regulation of energy metabolism in animals. However, both deficiency and excess supplementation of niacin can induce profound physiological disturbances in fish. The present study investigated the effect of niacin on energy metabolism and liver health in Nile tilapia (Oreochromis niloticus).
Ruixin Li, Jingwen Liu, Jiayong Liang, Lang Liang, Zexuan Kong, Tan Liu, Xiaojuan Liu, Fan Lin, Cuiying Chen, Zhenyu Du, Shuqi Wang, Mansour Torfi Mozanzadeh   +11 more
wiley   +1 more source

The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis [PDF]

, 1984
T. Norman Palmer, Margaret A. Caldecourt, Jon Warner, M C Sugden   +3 more
openalex   +1 more source

Activation of SIRT1 by Resveratrol Represses Transcription of the Gene for the Cytosolic Form of Phosphoenolpyruvate Carboxykinase (GTP) by Deacetylating Hepatic Nuclear Factor 4α*

Journal of Biological Chemistry, 2009
The SIRT1 activators isonicotinamide (IsoNAM), resveratrol, fisetin, and butein repressed transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C).
Jianqi Yang, Xiaoying Kong, M. Martins-Santos, G. Alemán, E. Chaco, G. Liu, Shwu‐Yuan Wu, D. Samols, Parvin Hakimi, C. Chiang, R. Hanson   +10 more
semanticscholar   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source

Thematic Minireview Series: A Perspective on the Biology of Phosphoenolpyruvate Carboxykinase 55 Years After Its Discovery*

Journal of Biological Chemistry, 2009
It is nowmore than 55 years since the mitochondrial form of phosphoenolpyruvate carboxykinase (GTP) (PEPCK; EC 4.1.1.32) from chicken liver was first reported by Utter and Kurahashi (1). Since that time, our understanding of the properties and biological
R. Hanson
semanticscholar   +1 more source

Aspects of the Control of Phosphoenolpyruvate Carboxykinase Gene Transcription*

Journal of Biological Chemistry, 2009
This article reviews our current understanding of factors that regulate transcription of the gene for PEPCK-C, focusing on the effect of methylation on gene expression. It also provides insight into the evolutionary status of the PEPCK-C gene.
Jianqi Yang, L. Reshef, Hanoch Cassuto, G. Alemán, R. Hanson   +4 more
semanticscholar   +1 more source

The isolation and functional identification of a phosphoenolpyruvate carboxykinase gene from Saccharina japonica

Aquaculture and Fisheries
Similar to other macroalgae, Saccharina japonica has CO2-concentrating mechanism (CCM) that allows high photosynthesis efficiency and elevates biomass. Phosphoenolpyruvate carboxykinase (PEPCK) in cytoplasm is an essential component of CCM.
Peichong Lin, Yatong Yao, Lijuan Lu, Yanhui Bi, Zhigang Zhou   +4 more
doaj   +1 more source

The Orphan Receptor COUP-TF Binds to a Third Glucocorticoid Accessory Factor Element within the Phosphoenolpyruvate Carboxykinase Gene Promoter [PDF]

, 1996
Donald K. Scott, John A. Mitchell, Daryl K. Granner   +2 more
openalex   +1 more source

AMP‐activated protein kinase counteracted the inhibitory effect of glucose on the phosphoenolpyruvate carboxykinase gene expression in rat hepatocytes [PDF]

, 2000
Aurélie Hubert, Annie Husson, Arlette Chédeville, Alain Lavoinne   +3 more
openalex   +1 more source

MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5. [PDF]

Oncogenesis, 2023
Cheung AH, Wong KY, Liu X, Ji F, Hui CH, Zhang Y, Kwan JS, Chen B, Dong Y, Lung RW, Yu J, Lo KW, Wong CC, Kang W, To KF.   +14 more
europepmc   +1 more source