The mitochondrial and cytosolic forms of avian phosphoenolpyruvate carboxykinase (GTP) are encoded by different messenger RNAs. [PDF]
Previous work from our laboratory (Watford, M., Hod, Y., Chiao, Y. B., Utter M. F., and Hanson R. W. (1981) J. Biol. Chem. 256, 10023-10027) indicated that in the chicken, hepatic phosphoenolpyruvate carboxykinase is in the mitochondria, whereas kidney contains both a mitochondrial and cytosolic form of the enzyme. In the present study the two forms of
Merton F. Utter+2 more
openaire +2 more sources
A graph-transformer for whole slide image classification [PDF]
Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However, patch-based methods introduce label noise during training by assuming that each patch is independent with the same ...
arxiv
Nucleotide sequence of the mRNA encoding the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) from the chicken. [PDF]
We have determined the sequence of the mRNA encoding cytosolic phosphoenolpyruvate carboxykinase (GTP) [GTP:oxaloacetate carboxy-lyase (transphosphorylating), EC 4.1.1.32] from the chicken and have deduced the primary structure of the protein. The message for the enzyme is 2762 bases long and encodes a protein of 622 amino acids with a molecular mass ...
Y Hod+4 more
openaire +3 more sources
Gravitational Thomas Precession and the Perihelion Advance of Mercury [PDF]
Gravitational Thomas Precession (GTP) is the name given to Thomas Precession when the acceleration is caused by a gravitational force field. The GTP gives a negative contribution of 7.163 arcsec/century for the anomalous perihelion advance of Mercury's orbit. This effect seems to be of some concern for the General Relativity.
arxiv
Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS) [PDF]
Phosphoenolpyruvate carboxykinase-1 (PCK1) is the rate-limiting enzyme in the hepatic gluconeogenic pathway. Studies have shown that overexpression of Pck1 in mice results in obesity-related traits and higher levels of physical activity (PA).
Anders Grontved+45 more
core +1 more source
The mRNA that codes for phosphoenolpyruvate carboxykinase accounts for approximately 0.2% of the protein synthesized in H4IIEC3 hepatoma cells maintained for 24 h in serum-free medium containing N6,O2'-dibutyryl cAMP and theophylline. This value decreases to 0.04% within 3 h after the addition of insulin.
Daryl K. Granner+3 more
openaire +3 more sources
Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor binding. [PDF]
The ability of a retinoic acid (RA) response element (RARE) in the phosphoenolpyruvate carboxykinase (PEPCK) gene promoter to mediate effects of either RA or thyroid hormone (T3) on gene expression was studied.
B M Forman+3 more
core +1 more source
Is there a Gravitational Thomas Precession ? [PDF]
Gravitational Thomas Precession (GTP) is the name given to Thomas Precession when the acceleration is caused by a gravitational force field. The contributio n of the GTP to the the anomalous perihelion advance of the orbit of Mercury is here estimated at $\dot{\tilde{\bf\omega}}_{GTP} = 21\cdot49 [ 1 + \frac{(\vec L \cdot \vec S)}{L^{2}} ] {arcsec ...
arxiv
Detector performance of the Gamma-ray Transient Monitor onboard DRO-A Satellite [PDF]
Gamma-ray Transient Monitor (GTM) is an all-sky monitor onboard the Distant Retrograde Orbit-A (DRO-A) satellite with the scientific objective of detecting gamma-ray transients ranging from 20 keV to 1 MeV. GTM is equipped with 5 Gamma-ray Transient Probe (GTP) detector modules, utilizing the NaI(Tl) scintillator coupled with a SiPM array.
arxiv +1 more source
The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism – insights from mathematical modeling [PDF]
Background Adaptation of the cellular metabolism to varying external conditions is brought about by regulated changes in the activity of enzymes and transporters.
Berndt, Nikolaus+2 more
core +1 more source