Cell–cell heterogeneity in phosphoenolpyruvate carboxylase biases early cell fate priming in Dictyostelium discoideum [PDF]
Glucose metabolism is a key factor characterizing the cellular state during multicellular development. In metazoans, the metabolic state of undifferentiated cells correlates with growth/differentiation transition and cell fate determination. Notably, the
Kenichi Abe +10 more
doaj +2 more sources
Lactobacillus acidophilus NS1 Reduces Phosphoenolpyruvate Carboxylase Expression by Regulating HNF4α Transcriptional Activity [PDF]
Probiotics have been known to reduce high-fat diet (HFD)-induced metabolic diseases, such as obesity, insulin resistance, and type 2 diabetes. We recently observed that Lactobacillus acidophilus NS1 (LNS1), distinctly suppresses increase of blood glucose
Sung-Soo Park, Garam Yang, Eungseok Kim
doaj +2 more sources
Anionic Phospholipids Induce Conformational Changes in Phosphoenolpyruvate Carboxylase to Increase Sensitivity to Cathepsin Proteases [PDF]
Phosphoenolpyruvate carboxylase (PEPC) is a cytosolic, homotetrameric enzyme that serves a variety of functions in plants, acting as the primary form of CO2 fixation in the C4 photosynthesis pathway (C4-PEPC).
Jacinto Gandullo +5 more
doaj +2 more sources
Phosphorylation of phosphoenolpyruvate carboxylase plays a key role in the control of plant metabolism. Phosphoenolpyruvate carboxylase kinase is a Ca2+‐independent enzyme that is activated by a process involving protein synthesis in response to a range ...
Gill, Aideen +5 more
core +8 more sources
Oligomerization and characteristics of phosphoenolpyruvate carboxylase in Synechococcus PCC 7002. [PDF]
Phosphoenolpyruvate carboxylase (PEPc) is an essential enzyme in plants. A photosynthetic form is present both as dimer and tetramer in C4 and CAM metabolism. Additionally, non-photosynthetic PEPcs are also present. The single, non-photosynthetic PEPc of
Durall C +3 more
europepmc +2 more sources
The Regulation of Phosphoenolpyruvate Carboxylase in Bryophyllum fedtschenkoi [PDF]
Phosphoenolpyruvate (PEP) carboxylase is the primary CO2-fixing enzyme in plants which exhibit crassulacean acid metabolism. The activity of this enzyme is under the control of an endogenous circadian rhythm.
Carter, Pamela J
core +6 more sources
Wild-type C. glutamicum ATCC 13032 is known to possess two enzymes with anaplerotic (C4-directed) carboxylation activity, namely phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx). On the other hand, C3-directed decarboxylation can be
Jannick Kappelmann +8 more
doaj +1 more source
The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes [PDF]
Objective Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects ...
Rui Pang +7 more
doaj +1 more source
Effects of exogenous melatonin on sugar and organic acid metabolism in early-ripening peach fruits.
To evaluated the effects melatonin (MT) on the sugar and acid metabolism of early-ripening peach fruits, the concentration of 150 μmol/L MT was sprayed on the leaves of peach trees.
Kexuan Zhou +8 more
doaj +1 more source
An in vitro Coupled Assay for PEPC with Control of Bicarbonate Concentration
Phosphoenolpyruvate carboxylase (PEPC) catalyzes a critical step in carbon metabolism in plants and bacteria, the irreversible reaction between bicarbonate and phosphoenolpyruvate to produce the C4 compound oxaloacetate.
Nicholas Moody +2 more
doaj +1 more source

