Results 131 to 140 of about 23,730,752 (211)
Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development. [PDF]
Pancreatic ductal adenocarcinoma (PDAC) remains a deadly disease with no efficacious treatment options. PDAC incidence is projected to increase, which may be caused at least partially by the obesity epidemic.
Eibl, Guido, Rozengurt, Enrique
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Exploring the impact of elevated muscle temperature on the rate and extent of postmortem pH decline in porcine skeletal muscle [PDF]
When an animal is harvested for meat, the resulting carcass is processed to provide safe and wholesome meat products for the consumer. One of these processing steps for pigs known as scalding involves heating the carcass in hot water (60ºC) in order to ...
Montgomery, Madison
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Detection of Mycobacterium lepromatosis in patients with leprosy in India
Madhvi Ahuja,1,* Mallika Lavania,1,* Itu Singh,1 Ravindra P Turankar,1 Seema Chhabra,2 Tarun Narang,3 Sunil Dogra,3 Utpal Sengupta1 1Department of Molecular Biology, Stanley Browne Laboratory, TLM Community Hospital, Delhi, India; 2Department of ...
Ahuja M+7 more
doaj
The PCK2-glycolysis axis assists three-dimensional-stiffness maintaining stem cell osteogenesis
Understanding mechanisms underlying the heterogeneity of multipotent stem cells offers invaluable insights into biogenesis and tissue development. Extracellular matrix (ECM) stiffness has been acknowledged as a crucial factor regulating stem cell fate ...
Zheng Li+6 more
doaj
Methyl- and acetyltransferases are stable epigenetic markers postmortem [PDF]
Postmortem brain tissue has been reported to be suitable to delineate regional pattern of possible disturbances underlying epigenetic functionality. However, from many parameters that have been detected in postmortem brain regions it is noteworthy that ...
Al-Saraj, Safa+13 more
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Innate immune responses are linked to key metabolic pathways, yet the proximal signaling events that connect these systems remain poorly understood. Here we show that phosphofructokinase 1, liver type (PFKL), a rate-limiting enzyme of glycolysis, is ...
Meiyue Wang+17 more
doaj +1 more source
The aim of this study was to determine changes in gene expression associated with glucose metabolism in the liver and soleus muscles of rats exposed to hypoxia to improve work capacity under high altitude conditions.
Yurie Hara, Nakamichi Watanabe
doaj
Summary: Aerobic glycolysis is critical for cancer progression and can be exploited in cancer therapy. Here, we report that the human carboxymethylenebutenolidase homolog (carboxymethylenebutenolidase-like [CMBL]) acts as a tumor suppressor by ...
Yingdan Huang+10 more
doaj
Glucagon and N,(6)O(2)-dibutyryl cyclic adenosine 3‘,5‘-cyclic monophosphate (Bt(2)cAMP) inhibit fatty acid synthesis from acetate by more than 90% and prevent citrate formation in chick hepatocytes metabolizing glucose.
S D Clarke, P A Watkins, M D Lane
doaj
Regulated acid-base transport in the collecting duct [PDF]
The renal collecting system serves the fine-tuning of renal acid-base secretion. Acid-secretory type-A intercalated cells secrete protons via a luminally expressed V-type H+-ATPase and generate new bicarbonate released by basolateral chloride/bicarbonate
Bourgeois, Soline+3 more
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