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Drought has been identified as a major threat for global crop production worldwide. Phosphofructokinase (PFK) is vital for sugar metabolism. During phosphorylation, plants have two enzymes: ATP-dependent phosphofructokinase (PFK) and pyrophosphate ...
Teame Gereziher Mehari+10 more
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Metabolic insights into phosphofructokinase inhibition in bloodstream-form trypanosomes
Previously, we reported the development of novel small molecules that are potent inhibitors of the glycolytic enzyme phosphofructokinase (PFK) of Trypanosoma brucei and related protists responsible for serious diseases in humans and domestic animals ...
Zandile Nare+6 more
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Chloroplast Phosphofructokinase [PDF]
Ammonium sulfate fractionation of an extract from the leaves of spinach (Spinacia oleracea L.) produced two fractions of phosphofructokinase activity, the first stimulated by inorganic phosphate and the second inhibited by inorganic phosphate. Only the second fraction was obtained from similar treatment of an extract of isolated spinach chloroplasts ...
Erwin Latzko, Grahame J. Kelly
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Ten 16-year-old trees were used as test materials to investigate the effect of foliar calcium fertilizer on the sugar content of ‘Feizixiao’ litchi (Litchi chinensis Sonn.) pulp. The experiment began 35 days after anthesis (DAA) in 2020 and 2021, and the
Junjie Peng+6 more
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Myostatin (MSTN) is a primary negative regulator of skeletal muscle mass and causes multiple metabolic changes. However, whether MSTN mutation affects heart morphology and physiology remains unclear.
Mingjuan Gu+14 more
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The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro+14 more
wiley +1 more source
The chloroplast primary metabolism is of central importance for plant growth and performance. Therefore, it is tightly regulated in order to adequately respond to multiple environmental conditions.
Natalia Hess+4 more
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Research progress on the mechanism of glycolysis in ovarian cancer
Glycolysis is the preferred energy metabolism pathway in cancer cells even when the oxygen content is sufficient. Through glycolysis, cancer cells convert glucose into pyruvic acid and then lactate to rapidly produce energy and promote cancer progression.
Chan Li+5 more
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Phosphofructokinase in Human Fetus [PDF]
The isozymic composition of phosphofructokinase (EC.2.7.1.11) from human fetal tissues has been investigated by immunological characterization, electrophoresis, purification, and SDS-polyacrylamide gel electrophoresis of the dissociated subunits. One of the characteristics of fetal tissues is the indiscriminate expression by all the cells of two or ...
Jean Claude Dreyfus+2 more
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To investigate the causes of the “sugar receding” in ‘Feizixiao’ litchi (Litchi chinensis Sonn.) pulp, the main sugar contents and sucrose metabolism enzyme activities were measured in pulp obtained in 2020 and 2021.
Junjie Peng+13 more
doaj +1 more source