Results 61 to 70 of about 28,503 (264)

Evaluation of Serum Pyruvate Kinase M2 and Key Glycolytic Signatures and Its Correlation with Phosphatidylinositol-3-kinase/Akt/Mammalian Target of Rapamycin Pathway in Women with Breast Carcinoma

Biomedical and Biotechnology Research Journal
Background: A desired target for cancer therapy is a cancer-specific metabolism which is associated with innate or acquired therapeutic resistance, malignancies, and aggressive cancer growth. Nevertheless, these cells utilize manifold metabolic routes to
Flama Monteiro, Vijith Vittal Shetty, Shilpa S. Shetty, Ranjitha Acharya, P. C. Suhasini, Suchetha Kumari Nalilu   +5 more
doaj   +1 more source

Effects of cadmium and mercury on the upper part of skeletal muscle glycolysis in mice.

PLoS ONE, 2014
The effects of pre-incubation with mercury (Hg(2+)) and cadmium (Cd(2+)) on the activities of individual glycolytic enzymes, on the flux and on internal metabolite concentrations of the upper part of glycolysis were investigated in mouse muscle extracts.
Maria José Ramírez-Bajo, Pedro de Atauri, Fernando Ortega, Hans V Westerhoff, Josep Lluis Gelpí, Josep J Centelles, Marta Cascante   +6 more
doaj   +1 more source

Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets

Food Safety and Health, EarlyView.
Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar, Nidhi N. Shah, Mehul R. Chorawala, Rekha Kaushik, Bhupendra Prajapati, Rahul Mehra   +5 more
wiley   +1 more source

Studies on Heart Phosphofructokinase

Journal of Biological Chemistry, 1966
Abstract Sheep heart phosphofructokinase was extracted from a sedimentable fraction of homogenates after incubation with ATP and MgSO4. The extracted enzyme was fully active and soluble. The enzyme was purified by a procedure which involved ethanol fractionation, extraction from the ethanol fraction, DEAE-cellulose chromatography, and ammonium sulfate ...
H. Mae Sprouse, Tag E. Mansour, Nabil Wakid   +2 more
openaire   +3 more sources

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

Glia, EarlyView.
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa, Jose L. Martin, Arzu Ulu, William Agnew‐Svoboda, Teresa Ubina, Martin M. Riccomagno, Todd A. Fiacco, Emma H. Wilson   +7 more
wiley   +1 more source

Inhibition of Rat Muscle and Liver Phosphofructokinases by High Doses of Ethanol

Biochemistry Research International, 2013
Activities of both rat muscle and liver phosphofructokinases are significantly inhibited after a single ethanol intake in the dose of 2.5 g per kg of body weight.
Sergey Vladimirovich Lelevich, Vladislav Victorovich Khrustalev, Eugene Victorovich Barkovsky   +2 more
doaj   +1 more source

Synthetic biology for medical biomaterials

Interdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu, Xiao‐Yun Huang, Jin‐Wei Dao, Da Xiao, Dai‐Xu Wei   +4 more
wiley   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

Molecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti, Martina Giuseffi, Eugenia Giglio, Graziella Marino, Marisabel Mecca   +4 more
wiley   +1 more source

Evidence for phosphorylation of yeast phosphofructokinase [PDF]

FEBS Letters, 1988
Radioactively labelled material from yeast cells grown in the presence of [32P]phosphate was specifically recognized by antibodies raised against yeast phosphofructokinase. Purified yeast phosphofructokinase was phosphorylated in a cyclic AMP‐independent manner by a protein kinase enriched from yeast extracts. This phosphorylation occurred specifically
Gerhard Kopperschläger, Klaus Huse, Bengt Jergil, Wolf-Dieter Schwidop   +3 more
openaire   +3 more sources

Defining the Molecular Impacts of Humalite Application on Field‐Grown Wheat (Triticum aestivum L.) Using Quantitative Proteomics

PROTEOMICS, EarlyView.
ABSTRACT Increasing global food production demands have resulted in increased fertilizer usage, causing detrimental environmental impacts. Biostimulants, such as humic substances, are currently being applied as a strategy to increase plant nutrient‐use efficiency and minimize environmental impacts within cropping systems.
Lauren E. Grubb, Mohana Talasila, Linda Y. Gorim, Richard Glen Uhrig   +3 more
wiley   +1 more source