Cell Proliferation, Volume 59, Issue 2, February 2026.The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu +5 more
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T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri +7 more
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PFK-1 Transcript Amounts in the Liver and Skeletal Muscle of Pigeons and Quail Acutely Exposed to High Embryonic Incubation Temperatures [PDF]
, 2018 The developing avian embryo is reliant on external sources of heat. Incubation temperatures above or below optimal alter development and metabolic function, and may compromise emergence and post-hatch adaptation.
Loveless, Michael
core
The kinetics of effector binding to phosphofructokinase. The binding of Mg2+-1,N6-ethenoadenosine triphosphate to the catalytic site [PDF]
, 1980 D. V. Roberts, George L. Kellett
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The use of the ethanol pathway in goldfish Carassius auratus (L.) following anoxia [PDF]
, 2001 Goldfish (Carassius auratus) were subjected, for a period of 6 weeks, to 2h progressive hypoxia followed by 6h anoxia in closed respirometers at 15 degree C.
Aleleye-Wokoma, L.P.
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Studies on the Fructose 1-Phosphate Kinase Activity of Rabbit Muscle Phosphofructokinase
Journal of Biological Chemistry, 1972 Abstract Pure phosphofructokinase from rabbit skeletal muscle is shown to catalyze the phosphorylation of fructose-1-P. The rate of fructose-1-P phosphorylation is about one-twentieth that of fructose-6-P phosphorylation at optimum conditions. The product of fructose-1-P phosphorylation was shown to be fructose 1,6-diphosphate by a number of criteria ...
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PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth
Cell ReportsSummary: Aerobic glycolysis, termed the Warburg effect, is one of the aberrant metabolic pathways in highly proliferating cells. Glycolysis provides glycolytic metabolites to support the generation of biomass, such as nucleotides, amino acids, and lipids.
Qingen Da +24 more
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Detection of Mycobacterium lepromatosis in patients with leprosy in India
Infection and Drug Resistance, 2018 Madhvi Ahuja,1,* Mallika Lavania,1,* Itu Singh,1 Ravindra P Turankar,1 Seema Chhabra,2 Tarun Narang,3 Sunil Dogra,3 Utpal Sengupta1 1Department of Molecular Biology, Stanley Browne Laboratory, TLM Community Hospital, Delhi, India; 2Department of ...
Ahuja M +7 more
doaj
Induction of Pyrophosphate-Dependent Phosphofructokinase in Watermelon (Citrullus lanatus) Cotyledons Coincides with Insufficient Cytosolic D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase to Sustain Gluconeogenesis [PDF]
, 1993 Anna‐Maria Botha, Frederik C. Botha
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Nature CommunicationsInnate immune responses are linked to key metabolic pathways, yet the proximal signaling events that connect these systems remain poorly understood. Here we show that phosphofructokinase 1, liver type (PFKL), a rate-limiting enzyme of glycolysis, is ...
Meiyue Wang +17 more
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