Results 141 to 150 of about 34,103 (213)

1-MCP maintains postharvest quality in winter jujube during low-temperature storage by regulating energy and sugar metabolism and enhancing antioxidant capacity

open access: yesFrontiers in Plant Science
This study investigates the effects of 1-methylcyclopropene (1-MCP) treatment on postharvest storage of winter jujube. The results indicate that after 1-MCP treatment, the pyruvate (PA) content in winter jujube decreased by 20% at 30 days compared to the
Wen Tang   +12 more
doaj   +1 more source

PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate

open access: yesNature Communications
Emerging evidence indicates that metabolic signals—including nutrient availability, biosynthetic intermediates, and energy balance—are linked to cell cycle progression.
Pianpian Lin   +11 more
doaj   +1 more source

Pharmacological Modulation of Mutant TP53 with Oncotargets Against Esophageal Cancer and Therapy Resistance

open access: yesBiomedicines
The prevalence and deaths from esophageal cancer (EC) have recently increased. Although therapeutic strategies depend on the EC stage and recurrence, such as surgical intervention, chemotherapy, radiation therapy, chemoradiation therapy, targeted therapy,
Pei-I Lin   +3 more
doaj   +1 more source

PFKL Inhibition by DT-13: A Novel Approach to Combat Hepatocellular Carcinoma

open access: yesInternational Journal of Hepatology
Aerobic glycolysis modulates proliferation, apoptosis, immune evasion, and targeted drug resistance in hepatocellular carcinoma (HCC) patients. Therefore, inhibiting aerobic glycolysis could represent a novel chemotherapeutic strategy for HCC.
Qiang Yu   +4 more
doaj   +1 more source

Comparisons of Phosphofructokinases-1 from Rabbit, Chicken, and Fish

open access: yesInternational Journal of Pharmaceutical Investigation, 2022
Patricia Gaitan-Hahn   +9 more
openaire   +1 more source

The mechanism of PFK-1 in the occurrence and development of bladder cancer by regulating ZEB1 lactylation

open access: yesBMC Urology
Background Bladder cancer (BC) is one of the most common malignancies of the genitourinary system. Phosphofructokinase 1 (PFK-1) is one of member of PFK, which plays an important role in reprogramming cancer metabolism, such as lactylation modification ...
Rong Wang   +5 more
doaj   +1 more source

Mechanisms of Energy Balance in Obesity

open access: yes, 1984
The proper understanding of obesity requires a multifaceted approach. Behavioral considerations of eating and activity patterns do not account for the large between- and within-subjects variance associated with the energy-balance equation.
McMinn, Mark R.
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