Background Sodium-glucose cotransporter (SGLT)2 inhibitors have displayed beneficial effects on the cardiovascular system in diabetes mellitus (DM) patients.
Eder Anderson Rodrigues +14 more
doaj +1 more source
Effect of ammonium concentration on alcoholic fermentation kinetics by wine yeasts for high sugar content [PDF]
Kinetics of alcoholic fermentation by Saccharomyces cerevisiae wine strains in a synthetic medium with high sugar content were established for different nitrogen initial content and are presented for 4 strains.
Fuster, André +3 more
core +2 more sources
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage. [PDF]
In metabolism, available free energy is limited and must be divided across pathway steps to maintain a negative ΔG throughout. For each reaction, ΔG is log proportional both to a concentration ratio (reaction quotient to equilibrium constant) and to a ...
Amador-Noguez, Daniel +6 more
core +2 more sources
Acclimation responses of Arabidopsis thaliana to sustained phosphite treatments [PDF]
Phosphite () induces a range of physiological and developmental responses in plants by disturbing the homeostasis of the macronutrient phosphate. Because of its close structural resemblance to phosphate, phosphite impairs the sensing, membrane transport,
Berkowitz, O. +7 more
core +2 more sources
Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. [PDF]
Label-free LC-MS/MS-based shot-gun proteomics was used to quantify the differential protein synthesis and metabolite profiling in order to assess metabolic changes during the development of citrus fruits.
Blumwald, Eduardo +8 more
core +3 more sources
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma
Background Infantile hemangioma (IH) is the most common tumor among infants, but the exact pathogenesis of IH is largely unknown. Our previous study revealed that glucose metabolism may play an important role in the pathogenesis of IH and that the ...
Kaiying Yang +7 more
doaj +1 more source
Background HIF-1 deficiency has marked effects on tumour glycolysis and growth. We therefore investigated the consequences of HIF-1 deficiency in mice, using the well established Hepa-1 wild-type (WT) and HIF-1β-deficient (c4) model.
Airley Rachel E +15 more
doaj +1 more source
Vanadate influence on metabolism of sugar phosphates in fungus Phycomyces blakesleeanus. [PDF]
The biological and chemical basis of vanadium action in fungi is relatively poorly understood. In the present study, we investigate the influence of vanadate (V5+) on phosphate metabolism of Phycomyces blakesleeanus.
Milan Žižić +6 more
doaj +1 more source
Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji +12 more
wiley +1 more source
SBML Reaction Finder: Retrieve and extract specific reactions from the BioModels database [PDF]
Summary: The SBML Reaction Finder (SRF) application leverages the deep semantic annotations in the BioModels database to provide efficient retrieval and extraction of individual reactions from SBML models.
Herbert M. Sauro, Maxwell L. Neal
core +2 more sources

