Muscle wasting in cancer cachexia: Mechanisms and the role of exercise
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento +2 more
wiley +1 more source
Decoding Membrane Lipids: Analytical Barriers and Technological Advances in Modern Lipidomics. [PDF]
Kim KH, Yoo BC.
europepmc +1 more source
Menopause and vascular endothelial health: Is it all about the oestrogen?
Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols +4 more
wiley +1 more source
Non-erythrocyte spectrin network preferentially stabilizes flat membrane and enhances cell stiffness. [PDF]
Komikawa T +8 more
europepmc +1 more source
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari +7 more
wiley +1 more source
Regulation of NRF2 by stably associated phosphoinositides and small heat shock proteins in response to stress. [PDF]
Chen C +6 more
europepmc +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
Circulating phospholipid species and internet addiction severity in Japanese adolescents: a pilot lipidomics study. [PDF]
Kawahara T +7 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Distinct phosphoinositide signatures orchestrate FcεRI versus MRGPRX2 mast cell secretion. [PDF]
Omari-Manaa S +4 more
europepmc +1 more source

