Results 111 to 120 of about 369,030 (389)

Oral Candida colonization in HIV-infected patients in Londrina-PR, Brazil: antifungal susceptibility and virulence factors

Journal of Infection in Developing Countries, 2015
Introduction: Host colonization by Candida species is an important predisposing factor to candidiasis, which seems to be more frequent in human immunodeficiency virus (HIV)-infected patients.
Suelen Balero de Paula, Alexandre Tadachi Morey, Jussevania Pereira Santos, Pollyanna M. C. dos Santos, Danielle G. Gameiro, Gilselena Kerbauy, Ester M. Sena, Luiz T. Ueda, Marcelo Carneiro, Phileno Pinge-Filho, Lucy Megumi Yamauchi, Sueli Fumie Yamada-Ogatta   +11 more
doaj   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

The substrate specificity of phospholipase A

Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1963
Investigations on variously modified analogues of phospholipids elucidated the following substrate characteristics for phospholipase A (Crotalus adamanteus). 1. 1. Within the class of α-phosphoglycerides l-isomers are readily hydrolysed, while d-α-phospholipids appeared not to be attacked. 2. 2.
Deenen, L.L.M. van, Haas, Gerard H. de
openaire   +3 more sources

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

Advanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang, Feifei Li, Libo Liu, Ziyu An, Hanzhong Luo, Huan Zhang, Rui Ma, Ruoxi Zhang, Qiong Dai, Mingduo Zhang, Jinfan Tian, Chaoyong Liu, Xiantao Song, Yunfeng Lu   +13 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Designing New Natural‐Mimetic Phosphatidic Acid: A Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research

Angewandte Chemie, EarlyView.
We report the role of the fatty acyl chains in biological activities of phosphatidic acids (PA). Several PA probes having two different fatty acyl chains were synthesized through a multi‐steps synthesis and bearing various fluorophores or photo‐cross‐linkers (PCL).
Antoine Schlichter, Alexander Wolf, Thomas Ferrand, Aurelien Cocq, Lina Riachy, Steven Vertueux, Brice Beauvais, Marine Courvalet, Paul‐Joël Henry, Emeline Tanguy, Louis Gonzales, Rémy Ferlet, Fanny Laguerre, Charles Decraene, Alexia Pellissier, Muriel Sebban, Cyrille Sabot, Lydie Jeandel, Sarah Cianférani, Jean‐Marc Strub, Magalie Bénard, Victor Flon, Valérie Peulon‐Agasse, Pascal Cardinael, Stéphane Ory, Stéphane Gasman, Pierre‐Yves Renard, Maïté Montero‐Hadjadje, Nicolas Vitale, Sébastien Balieu   +29 more
wiley   +2 more sources

The pathobiology of Neisseria gonorrhoeae lower female genital tract infection

Frontiers in Cellular and Infection Microbiology, 2011
Infection and disease associated with Neisseria gonorrhoeae, the gonococcus, continue to be a global health problem. Asymptomatic and subclinical gonococcal infections occur at a high frequency in females; thus, the true incidence of N.
Jennifer L Edwards, Jennifer L Edwards, Emily K. Butler   +2 more
doaj   +1 more source

Patatin-Related Phospholipase AtpPLAIIIα Affects Lignification of Xylem in Arabidopsis and Hybrid Poplars

Plants, 2020
Lipid acyl hydrolase are a diverse group of enzymes that hydrolyze the ester or amide bonds of fatty acid in plant lipids. Patatin-related phospholipase AIIIs (pPLAIIIs) are one of major lipid acyl hydrolases that are less closely related to potato tuber
Jin Hoon Jang, Ok Ran Lee
doaj   +1 more source

The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells [PDF]

, 1992
Thyrotropin-releasing hormone stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) in GH3 cell membranes. The stimulation of the phosphoinositide phospholipase C (PI/PLC) activity can be blocked by incubation of GH3 membranes with ...
Aragay, Anna M., Katz, Arieh, Simon, Melvin I.   +2 more
core  

Phospholipase A2 as a mechanosensor

Biophysical Journal, 1995
Osmotic swelling of large unilamellar vesicles (LUVs) causes membrane stretching and thus reduces the lateral packing of lipids. This is demonstrated to modulate strongly the catalytic activity of phospholipase A2 (PLA2) toward a fluorescent phospholipid, 1-palmitoyl-2-[(6-pyren-1-yl)]decanoyl-sn-glycero-3-phosphocholine (PPDPC) residing in LUVs ...
Paavo K.J. Kinnunen, Jukka Y. A. Lehtonen   +1 more
openaire   +3 more sources