Germinated legumes for improving nutritional and technological quality of fortified cakes, with further enhancement using phospholipase and SSL. [PDF]
NPJ Sci FoodAta SM, Hussein AMS, Mostafa S.
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British Journal of Pharmacology, EarlyView.Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
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The role of lysophosphatidic acid metabolism in castration-resistant prostate cancer progression. [PDF]
Front OncolFeng J, Liu J, He Y.
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Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes
British Journal of Pharmacology, EarlyView.Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
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ApoJ regulates endothelial lipase activity and stability. [PDF]
Protein SciJean-Baptiste UL +5 more
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British Journal of Pharmacology, EarlyView.Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar +6 more
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Post-heparin plasma lipase activities in patients with severe hypertriglyceridemia treated with evinacumab. [PDF]
J Lipid ResVitali C +5 more
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Functional screen for subtype specificity of voltage sensor–targeted Kv7 potentiators
British Journal of Pharmacology, EarlyView.Background and Purpose Voltage‐gated Kv7 (potassium channel subfamily Q [KCNQ]) potassium channels are powerful modulators of neuronal excitability. ICA‐069673 is a N‐aryl benzamide drug that targets the voltage‐sensing domain (VSD) of Kv7.2 with strong selectivity over Kv7.3 or Kv7.5, but the molecular basis of this selectivity remains poorly ...
Richard Kanyo +6 more
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Lysophosphatidylethanolamine (LysoPE) in health and disease: a narrative review of its pathophysiological mechanisms and translational potential as a biomarker. [PDF]
Front Cell Dev BiolWang KM, Shang XY, Shi XG.
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Critique of a Radically New Model for Plasma Membrane Bilayer Organization. [PDF]
BioessaysLange Y, Steck TL.
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