Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet+6 more
wiley +1 more source
Case report: Coexistence of optic neuritis and primary anti-PLA2R-positive membranous nephropathy. [PDF]
Wang X, Zeng Y, Zhao Y, Li B, Yang J.
europepmc +1 more source
Central mechanisms of emesis: A role for GDF15
Abstract Background Nausea and emesis are ubiquitously reported medical conditions and often present as treatment side effects along with polymorbidities contributing to detrimental life‐threatening outcomes, such as poor nutrition, lower quality of life, and unfavorable patient prognosis.
Tito Borner+2 more
wiley +1 more source
Synergistic antifungal effects and mechanisms of amantadine hydrochloride combined with azole antifungal drugs on drug-resistant <i>Candida albicans</i>. [PDF]
Li X+5 more
europepmc +1 more source
Transabdominal photobiomodulation applications: A systematic review and meta‐analysis
Summary Introduction The escalating prevalence of obesity presents a multifaceted challenge involving genetic, environmental, and behavioral factors, with significant public health implications. Photobiomodulation (PBM) may positively influence metabolic activities in adipose cells and regulate inflammation, potentially impacting obesity.
Ana M. Jiménez‐García+4 more
wiley +1 more source
Plant-Derived Lapachol Analogs as Selective Metalloprotease Inhibitors Against <i>Bothrops</i> Venom: A Review. [PDF]
Melo PA+11 more
europepmc +1 more source
Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai+4 more
wiley +1 more source
Epitope-based antibody development against metalloproteinases and phospholipases A<sub>2</sub> from <i>Deinagkistrodon acutus</i> venom. [PDF]
Zhu H+6 more
europepmc +1 more source
Effect of Phospholipase C Hydrolysis of Membrane Phospholipids on Membranous Enzymes
Richard D. Mavis+2 more
openalex +1 more source