Results 61 to 70 of about 22,854,117 (232)

Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]

, 1987
The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M., Kurtz, Armin, Kühn, K., Pfeilschifter, J.   +3 more
core   +1 more source

Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones [PDF]

, 2013
Neurodegenerative diseases are characterized by progressive degeneration of selective neurones in the nervous system, but the underlying mechanisms involved in neuroprotection and neurodegeneration remain unclear.
Abisambra, Ambruso, Andersen, Antunes, Aslihan Ugun-Klusek, Beal, Bedford, Beranova-Giorgianni, Bhandary, Chandra, Chatterjee, Choy, Croisier, Demasi, Dennissen, Ding, Dumitru Constantin-Teodosiu, Ebrahimi-Fakhari, Ellen Billett, Erdelmeier, Federico, Ferreiro, Fisher, Fisher, Fisher, Fisher, Freeman, Fribley, Gandhi, Goemaere, Goldberg, Grune, Hussong, Jain, Jamal Elkharaz, James Lowe, Jin, Jourdain, Kalyanaraman, Kamphuis, Karen Lawler, Kastle, Kim, Krapfenbauer, Leavey, Leuner, Lien, Ling, Lowe, Lynn Bedford, Malhotra, Manevich, Manevich, Mayford, Middeldorp, Morawe, Omura, Orre, Paine, Palacino, Pekny, Pickering, Pickering, Pimentel, Power, Power, Pratico, R John Mayer, Rabilloud, Samali, Schapira, Shringarpure, Slater, Sofroniew, Sofroniew, Strey, Tannu, Tsien, Varcin, Wang, Wang, Wang, Wang, Wang, Wang, Xiong, Yata, Zhang, Zoltewicz   +88 more
core   +1 more source

Phospholipase A(2) in vascular disease.

Circulation Research, 2001
Secretory phospholipase A(2) (PLA(2)) can be proatherogenic both in the circulation and in the arterial wall. In blood plasma, PLA(2) can modify the circulating lipoproteins and so induce formation of small dense LDL particles, which are associated with ...
Eva Hurt-Camejo, Germán Camejo, H. Peilot, Katarina Öörni, Petri T. Kovanen   +4 more
semanticscholar   +1 more source

Multiplex ligation-dependent probe amplification (MLPA) analysis is an effective tool for the detection of novel intragenic PLA2G6 mutations: Implications for molecular diagnosis [PDF]

, 2010
Phospholipase associated neurodegeneration (PLAN) comprises a heterogeneous group of autosomal recessive neurological disorders caused by mutations in the PLA2G6 gene. Direct gene sequencing detects 85% mutations in infantile neuroaxonal dystrophy.
Brady, Angela F, Crompton, Danielle, De Gressi, Susanna, Foster, Kathleen, Hardy, Carol, Hughes, Imelda, Kurian, Manju A, Lunt, Peter, MacPherson, Lesley, Maher, Eamonn R, McDonald, Fiona, Morgan, Neil V, Pike, Michael G, Rehal, Pauline K, Smith, Matthew   +14 more
core   +1 more source

Study of the influence of various physiologically active substances on changes in the lipid composition and phospholipase activity of damaged somatic nerves [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
The changes in lipid composition and phospholipase activity in damaged somatic nerves were studied against the background of the action of potassium hyaluronate and insulin-like growth factor-1.
Revin, Viktor V., Parchaykina, Marina V., Chudaikina, Elena V., Revina, Elvira S., Molchanov, Ivan D., Simakova, Milena A., Zavarykina, Anastasia Vyacheslavovna, Grunyushkin, Igor P., Devyatkin, Arkadiy А.   +8 more
doaj   +1 more source

Fungistatic effect of Gracilaria verrucosa on phospholipase enzymes and the cell surface hydrophobicity of Candida albicans

Dental Journal
Background: Candida albicans (C. albicans) was reported as a primary cause of oral candidiasis. Phospholipase enzymes and cell surface hydrophobicity (CSH) are involved in the pathogenesis of its infection. Gracilaria verrucosa (G. verrucosa) is reported
Basri A. Gani, Ridha Andayani, Fitri Yunita Batubara, Ifwandi Ifwandi, Dharli Syafriza, Muhammad Mas'ud Herlambang, Shiti Alya Fathirah, Ayudia Rifki   +7 more
doaj   +1 more source

Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus.

European Journal of Biochemistry, 2004
Phaiodactylipin was purified from the venom of the scorpion Anuroctonus phaiodactylus. It is the first protein to be purified from a scorpion of the family Iuridae and has a molecular mass of 19 172 atomic mass units.
N. A. Valdez-Cruz, C. Batista, L. Possani   +2 more
semanticscholar   +1 more source

Elicitor-activated phospholipase A(2) generates lysophosphatidylcholines that mobilize the vacuolar H(+) pool for pH signaling via the activation of Na(+)-dependent proton fluxes.

The Plant Cell, 2002
The elicitation of phytoalexin biosynthesis in cultured cells of California poppy involves a shift of cytoplasmic pH via the transient efflux of vacuolar protons.
K. Viehweger, B. Dordschbal, W. Roos
semanticscholar   +1 more source

Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications [PDF]

, 2019
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation and fibrillation makes ...
Alza, Natalia Paola, Conde, Melisa Ailén, Iglesias González, Pablo Andrés, Salvador, Gabriela Alejandra, Uranga, Romina Maria   +4 more
core   +1 more source

Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A2 Action at the Single Molecule Level [PDF]

, 2009
We monitored the action of phospholipase A2 (PLA2) on L- and D-dipalmitoylphosphatidylcholine (DPPC) Langmuir monolayers by mounting a Langmuir-trough on a wide-field fluorescence microscope with single molecule sensitivity.
Apitz-Castro, Biltonen, Bonsen, Burack, Burack, Chiu, Dahmen-Levison, Dimitrios Stamou, Flors, Grainger, Grainger, Grandbois, Gudmand, Heimburg, Hiroshi Uji-I, Hønger, Johan Hofkens, Kalina Peneva, Klaus Müllen, Klopfer, Leidy, Li, Maloney, Maloney, Margineanu, Martin Gudmand, McConlogue, Mouritsen, Nielsen, Nielsen, Nikos S. Hatzakis, Op den Kamp, Pattus, Pattus, Peneva, Rocha, Saari, Schütz, Simonsen, Six, Sonesson, Susana Rocha, Thomas Bjørnholm, Thomas Heimburg, Verger, Webb, Zhou   +46 more
core   +3 more sources