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[Pancreatic phospholipase A2].
Nihon rinsho. Japanese journal of clinical medicine, 1996Pancreatic phospholipase A2 is one of the digestive enzymes in pancreatic juice. As there are other phospholipase activities in the serum, serum pancreatic phospholipase A2 is measured by immunoassay. A decrease in the serum level of this enzyme is significantly correlated with pancreatic dysfunction demonstrated by the secretin test.
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2015
Phospholipase A2s (PLA2s) are a group of enzymes that hydrolyze the sn-2 position of phospholipids to generate fatty acids and lysophospholipids, which serve as lipid mediators or their precursors. Mammalian genomes encode genes for more than 30 PLA2s or related enzymes, which are subdivided into several groups on the basis of their structures ...
Makoto Murakami, Yoshitaka Taketomi
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Phospholipase A2s (PLA2s) are a group of enzymes that hydrolyze the sn-2 position of phospholipids to generate fatty acids and lysophospholipids, which serve as lipid mediators or their precursors. Mammalian genomes encode genes for more than 30 PLA2s or related enzymes, which are subdivided into several groups on the basis of their structures ...
Makoto Murakami, Yoshitaka Taketomi
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Phospholipase A2 — Regulation and inhibition
Klinische Wochenschrift, 1989Phospholipase A2 (PLA2) has been implicated in the pathogenesis of different diseases. Thus, the pharmacological intervention of PLA2 activity by specific inhibitors is of great therapeutical value in ameliorating pathological conditions. Despite a great number of published data regarding PLA2 inhibitors none has reached clinical application.
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Cytosolic phospholipase A2 and lysophospholipid acyltransferases.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2019Y. Kita, H. Shindou, Takao Shimizu
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1999
Platelet activation begins with the binding of an agonist to the cell surface, leading to aggregation, secretion and clot formation. The thromboxane A2 (TxA2 ) formed from arachidonic acid (AA, ω-6) serves as an important intracellular mediator in platelet function (1–5).
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Platelet activation begins with the binding of an agonist to the cell surface, leading to aggregation, secretion and clot formation. The thromboxane A2 (TxA2 ) formed from arachidonic acid (AA, ω-6) serves as an important intracellular mediator in platelet function (1–5).
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Murine macrophage phospholipase A2
Biochemical Society Transactions, 1991Judith E Meats, Leslie Steele
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