Results 101 to 110 of about 117,202 (259)
Phosphatidic acid, phospholipase D and tumorigenesis
Advances in Biological Regulation, 2014 Phospholipase D (PLD) is a membrane protein with a double role: maintenance of the structural integrity of cellular or intracellular membranes and involvement in cell signaling through the product of the catalytic reaction, PA, and through protein-protein interaction with a variety of partners.
openaire +2 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
Medicinal Research Reviews, EarlyView.ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
wiley +1 more source
Organelle-Selective Membrane Labeling through Phospholipase D-Mediated Transphosphatidylation. [PDF]
JACS Au, 2022 Chiu DC, Baskin JM.
europepmc +1 more source
Neuroprotection, EarlyView.Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu +7 more
wiley +1 more source
Genome-wide identification, structural homology analysis, and evolutionary diversification of the phospholipase D gene family in the venom gland of three scorpion species. [PDF]
BMC Genomics, 2023 Baradaran M, Salabi F.
europepmc +1 more source
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
PROTEOMICS, EarlyView.ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
Protein salvage and repurposing in evolution: Phospholipase D toxins are stabilized by a remodeled scrap of a membrane association domain. [PDF]
Protein Sci, 2023 Cordes MHJ +3 more
europepmc +1 more source
Soybean induced resistance to Spodoptera eridania herbivory
Pest Management Science, EarlyView.SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza +6 more
wiley +1 more source