Results 121 to 130 of about 122,680 (213)

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Spider venom phospholipase D toxin structure: Interfacial binding site, mechanism, activation, and head group preference. [PDF]

Proc Natl Acad Sci U S A
Sundman AK, Binford GJ, Montfort WR, Cordes MHJ.   +3 more
europepmc   +1 more source

Cellular Immunity in Mice Vaccinated with Recombinant Phospholipase D Toxoid of Hemiscorpius lepturus Scorpion. [PDF]

J Arthropod Borne Dis, 2022
Safari-Foroushani N, Modarressi MH, Pooshang Bagheri K, Behdani M, Shahbazzadeh D.   +4 more
europepmc   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Correction to "Development and Evaluation of Indole-Based Phospholipase D Inhibitors for Lung Cancer Immunotherapy". [PDF]

J Med Chem
Song D, Lim SH, Kim Y, Lee H, Kim T, Lim H, Min DS, Han G.   +7 more
europepmc   +1 more source

Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina. [PDF]

J Lipid Res, 2022
Barber CN, Goldschmidt HL, Lilley B, Bygrave AM, Johnson RC, Huganir RL, Zack DJ, Raben DM.   +7 more
europepmc   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source

x-Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca²⁺-Stabilized Expanded Active-Site Cleft Adapted for Phospholipid Binding. [PDF]

Proteins
Yasutake Y, Hirata T, Nomura S, Konishi K, Yoneda K, Sakasegawa SI, Sakuraba H.   +6 more
europepmc   +1 more source

Reduction of Membrane Lipid Metabolism in Postharvest Hami Melon Fruits by n-Butanol to Mitigate Chilling Injury and the Cloning of Phospholipase D-β Gene. [PDF]

Foods, 2023
Huang S, Bi Y, Li H, Liu C, Wang X, Wang X, Lei Y, Zhang Q, Wang J.   +8 more
europepmc   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source