Results 141 to 150 of about 117,202 (259)

Enhanced immunogenicity of COVID-19 RBD fused to mutant scorpion's phospholipase D for vaccine development. [PDF]

New Microbes New Infect
Zareinejad MR, Behdani M, Goodarzi MT, Oghalaie A, Hosseininejad-Chafi M, Pooshang-Bagheri K, Shahbazzadeh D.   +6 more
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Safety evaluation of the food enzyme phospholipase D from the non-genetically modified <i>Streptomyces netropsis</i> strain DSM 40093. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Fernàndez-Fraguas C, Aguilera J, Andryszkiewicz M, Cavanna D, Liu Y.   +17 more
europepmc   +1 more source

A secretory phospholipase D hydrolyzes phosphatidylcholine to suppress rice heading time. [PDF]

PLoS Genet, 2021
Qu L, Chu YJ, Lin WH, Xue HW.
europepmc   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source

Corynebacterium pseudotuberculosis phospholipase D targets mitochondrial sphingomyelin and induces NLRP3-GSDMD axis-mediated pyroptosis in macrophages to promote infection. [PDF]

Vet Res
Li X, Lv H, Wu C, Li H, Yi W, Niu X, Peng Q, Meng C, Yuan Y, Tian S, Wang Z, Fang R, Zhou Z.   +12 more
europepmc   +1 more source

Genome-wide identification and expression analysis of phospholipase D gene in leaves of sorghum in response to abiotic stresses. [PDF]

Physiol Mol Biol Plants, 2022
Wei J, Shao W, Liu X, He L, Zhao C, Yu G, Xu J.   +6 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Abscisic Acid, Microtubules and Phospholipase D-Solving a Cellular Bermuda Triangle. [PDF]

Int J Mol Sci
Liu X, Riemann M, Nick P.
europepmc   +1 more source

Improving Both the Thermostability and Catalytic Efficiency of Phospholipase D from Moritella sp. JT01 through Disulfide Bond Engineering Strategy. [PDF]

Int J Mol Sci, 2022
Li L, Mao X, Deng F, Wang Y, Wang F.
europepmc   +1 more source