Results 161 to 170 of about 117,202 (259)

Structural and Energetic Evidence Supports the Non-Covalent Phosphate Cyclization by the Class II Phospholipase D from Loxosceles intermedia. [PDF]

Toxins (Basel)
Gismene C, Ruggiero Bachega JF, Doherty DZ, Veiga SS, Arni RK, Hernández González JE.   +5 more
europepmc   +1 more source

Genome-Wide Analysis and Expression Profiling of the Phospholipase D Gene Family in Solanum tuberosum. [PDF]

Biology (Basel), 2021
Li L, Zhang C, Zhang M, Yang C, Bao Y, Wang D, Chen Q, Chen Y.   +7 more
europepmc   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, EarlyView.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Targeting Phospholipase D Pharmacologically Prevents Phagocytic Function Loss of Retinal Pigment Epithelium Cells Exposed to High Glucose Levels. [PDF]

Int J Mol Sci, 2022
Bermúdez V, Tenconi PE, Echevarría MS, Asatrian A, Calandria JM, Giusto NM, Bazan NG, Mateos MV.   +7 more
europepmc   +1 more source

Phospholipase D Family Member 4 Regulates Microglial Phagocytosis and Remyelination via the AKT Pathway in a Cuprizone-Induced Multiple Sclerosis Mouse Model. [PDF]

CNS Neurosci Ther
Sun R, Ma T, Zhao Z, Gao Y, Feng J, Yang X.   +5 more
europepmc   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, EarlyView.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source

Catalytically active prokaryotic Argonautes employ phospholipase D family proteins to strengthen immunity against different genetic invaders. [PDF]

mLife
Cheng F, Wu A, Li Z, Xu J, Cao X, Yu H, Liu Z, Wang R, Han W, Xiang H, Li M.   +10 more
europepmc   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source

Role of the <i>Yersinia pestis</i> phospholipase D (Ymt) in the initial aggregation step of biofilm formation in the flea. [PDF]

mBio
Jarrett CO, Leung JM, Motoshi S, Sturdevant DE, Zhang Y, Hoyt FH, Hinnebusch BJ.   +6 more
europepmc   +1 more source