Role of the <i>Yersinia pestis</i> phospholipase D (Ymt) in the initial aggregation step of biofilm formation in the flea. [PDF]
Jarrett CO +6 more
europepmc +1 more source
Involvement of phospholipase A2 in the response of Solanum species to an elicitor from Phytophthora infestans [PDF]
Maciejewska, Urszula +5 more
core +1 more source
Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley +1 more source
Whole-Cell Display of Phospholipase D in <i>Escherichia coli</i> for High-Efficiency Extracellular Phosphatidylserine Production. [PDF]
Sun B +6 more
europepmc +1 more source
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar +6 more
wiley +1 more source
Inhibition of phospholipase D promotes neurological function recovery and reduces neuroinflammation after spinal cord injury in mice. [PDF]
Ke H +14 more
europepmc +1 more source
Corrigendum to: The transcription factors slug (SNAI2) and snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion. [PDF]
europepmc +1 more source
Functional screen for subtype specificity of voltage sensor–targeted Kv7 potentiators
Background and Purpose Voltage‐gated Kv7 (potassium channel subfamily Q [KCNQ]) potassium channels are powerful modulators of neuronal excitability. ICA‐069673 is a N‐aryl benzamide drug that targets the voltage‐sensing domain (VSD) of Kv7.2 with strong selectivity over Kv7.3 or Kv7.5, but the molecular basis of this selectivity remains poorly ...
Richard Kanyo +6 more
wiley +1 more source
Immobilization of Phospholipase D on Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-Graphene Oxide Nanocomposites: A Strategy to Improve Catalytic Stability and Reusability in the Efficient Production of Phosphatidylserine. [PDF]
Shang H, Wang J, Guo B, Zhu H, Li H.
europepmc +1 more source
From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang +9 more
wiley +1 more source

