Results 211 to 220 of about 116,973 (287)

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Measurements of Phospholipases A₂, C, and D (PLA₂, PLC, and PLD): In Vitro Microassays, Analysis of Enzyme Isoforms, and Intact-Cell Assays

, 2003
Julián Gómez-Cambronero, Joel Horwitz, R.I. Sha’afi   +2 more
openalex   +2 more sources

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

Allergy, EarlyView.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger, Carolin Költgen, Magda Babina, Peter Wolf   +3 more
wiley   +1 more source

Analyses for the mechanisms of <i>N</i>-acylethanolamine biosynthesis in peripheral tissues using mice lacking <i>N</i>-acylethanolamine-forming phospholipase D-type enzyme

, 2019
Kazuhito Tsuboi, Manami Inoue, Yoko Okamoto, Mayumi Hidaka, Toru Uyama, Toshihiko Tsutsumi, Tamotsu Tanaka, Yasuo Okamoto, Natsuo Ueda, Akira Tokumura   +9 more
openalex   +2 more sources

New Allergens Approved by the WHO/IUIS Allergen Nomenclature Sub‐Committee in 2021–2024 and Their Significance for Future Diagnostics, Regulation, and Research. An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT The WHO/IUIS Allergen Nomenclature Sub‐Committee is an international body of experts that maintains the systematic nomenclature of allergenic proteins by assigning official names to newly identified allergens submitted by researchers. Here, we summarize the data on new allergens approved between 2021 and 2024.
Christian Radauer, Gabriele Gadermaier, Richard E. Goodman, Alain Jacquet, Uta Jappe, Andreas L. Lopata, Anna Pomés, Monika Raulf, Keity S. Santos, Josefina Zakzuk, Yuzhu Zhang, Joana Vitte, on behalf of the WHO/IUIS Allergen Nomenclature Sub‐Committee   +12 more
wiley   +1 more source

Investigation of potential roles of Phospholipase D in Arabidopsis thaliana seed oil accumulation

, 2009
Yuanyuan Yu
openalex   +1 more source

Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food

Allergy, EarlyView.
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger   +7 more
wiley   +1 more source

Sugar-dependent regulation of the phospholipase D activity in oat seedlings

, 2019
A. М. Каbachevskaya, S. V. Sukhaveyeva, I. D. Volotovski   +2 more
openalex   +2 more sources

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source