Results 201 to 210 of about 144,128 (376)

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva   +5 more
wiley   +1 more source

Spectrophotometric determination of lipases, lysophospholipases, and phospholipases

open access: yesJournal of Lipid Research, 1984
Spectrophotometric techniques for determining the activities of lipases, lysophospholipases, and phospholipases are reviewed. These methods involve the use of thioester substrate analogs as well as omega-nitrophenyl derivatives of the corresponding ...
A A Farooqui   +4 more
doaj  

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

open access: yesMolecular Nutrition &Food Research, EarlyView.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela   +5 more
wiley   +1 more source

Acetylcholinesterase Inhibition and Antioxidant Activity of DHA‐Disubstituted Phospholipids

open access: yesMolecular Nutrition &Food Research, EarlyView.
1,2‐Di‐DHA‐PC phospholipids in nutraceutical form may cross the blood‐brain barrier and inhibit acetylcholinesterase (AChE) activity, with an efficacy similar to galantamine. This suggests their potential as neuroprotective agents in the treatment of Alzheimer's disease.
Ernestina Garcia‐Quinto   +4 more
wiley   +1 more source

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