Results 41 to 50 of about 144,128 (376)
Phospholipases in Gliomas: Current Knowledge and Future Perspectives from Bench to Bedside
Phospholipases are essential intermediaries that work as hydrolyzing enzymes of phospholipids (PLs), which represent the most abundant species contributing to the biological membranes of nervous cells of the healthy human brain.
Maria Vittoria Marvi+15 more
doaj +1 more source
Hereditary spastic paraplegia (HSP), is a heterogeneous group of corticospinal tract disorders leading to progressive lower limb weakness and spasticity.
B Jude Antonieo Raja+3 more
doaj +1 more source
Acinetobacter baumannii Virulence Is Mediated by the Concerted Action of Three Phospholipases D
Acinetobacter baumannii causes a broad range of opportunistic infections in humans. Its success as an emerging pathogen is due to a combination of increasing antibiotic resistance, environmental persistence and adaptation to the human host.
J. Stahl+4 more
semanticscholar +1 more source
Phospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in ...
Richmond, Gregory S., Smith, Terry K.
openaire +2 more sources
Introduction to Thematic Review Series: Phospholipases: Central Role in Lipid Signaling and Disease
Hydrolases constitute an enormous proportion of our enzymes, being responsible for the initiation of most digestive processes and numerous physiological processes.
E. Dennis
semanticscholar +1 more source
2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. [PDF]
Cytosolic phospholipase A2 (GIVA cPLA2) is the only PLA2 that exhibits a marked preference for hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid and lysophospholipids and giving rise to the generation of ...
Barbayianni, Efrosini+10 more
core +1 more source
Role of phospholipases in adrenal steroidogenesis.
Phospholipases are lipid-metabolizing enzymes that hydrolyze phospholipids. In some cases, their activity results in remodeling of lipids and/or allows the synthesis of other lipids.
W. Bollag
semanticscholar +1 more source
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors
Membranes allow the compartmentalization of biochemical processes and are therefore fundamental to life. The conservation of the cellular membrane, combined with its accessibility to secreted proteins, has made it a common target of factors mediating ...
Alistair B. Russell+7 more
semanticscholar +1 more source
Partial Characterization of Venom from the Colombian Spider Phoneutria Boliviensis (Aranae:Ctenidae)
We report on the first studies on the characterization of venom from Phoneutria boliviensis (Aranae:Ctenidae) (F. O. Pickard-Cambridge, 1897), done with Colombian species.
Sebastian Estrada-Gomez+3 more
doaj +1 more source
Assessment of different Enzymatic Virulence Traits contributing to pathogenicity of Candida Albicans
Background: Candidiasis is regarded as one of the frequently occurring fungal infections of humans elicited by yeast that belongs to the genus Candida. Among the different species of Candida, Candida albicans is the most pathogenic specie.
Sadia Nazeer+6 more
doaj +1 more source