Results 101 to 110 of about 25,150,915 (368)

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

open access: yesToxins, 2020
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
Luciana A. Freitas-de-Sousa   +14 more
doaj   +1 more source

Multiple and Alternative Sites Make Tau Protein an Adaptable Sticky Surface for the SH3 Domain of Fyn Kinase

open access: yesAngewandte Chemie International Edition, Accepted Article.
The interaction between the microtubule associated protein Tau and the tyrosine kinase Fyn is believed to play a pivotal role in the early stage of Alzheimer’s disease (AD). Previous studies have identified the SRC Homology 3 (SH3) domain of Fyn as the binding receptor of several proline‐rich motifs in Tau.
Roberto Tira   +8 more
wiley   +1 more source

A Piece of the Lepton Theory from a Probability [PDF]

open access: yesarXiv, 2001
A masses of a leptons deduced from a representation of a probability density vector by a spinors. A massive W and Z bosons and a massless A boson are obtained from a transformations for which a density vector is invariant.
arxiv  

On a question of A. Balog [PDF]

open access: yesarXiv, 2015
We give a partial answer to a conjecture of A. Balog, concerning the size of AA+A, where A is a finite subset of real numbers. Also, we prove several new results on the cardinality of A:A+A, AA+AA and A:A + A:A.
arxiv  

Mammalian Phospholipase A2: Phospholipase A2 Receptor

open access: yesBiological and Pharmaceutical Bulletin, 2004
The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family such as the mannose receptor. PLA2R regulates a variety of biological responses elicited by secretory phospholipase A2s (sPLA2s). Group IB sPLA2 acts as an endogenous ligand to induce cell proliferation and lipid mediator production ...
openaire   +4 more sources

The emerging roles of PAF acetylhydrolase

open access: yesJournal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre   +2 more
doaj  

Hypotensive Snake Venom Components—A Mini-Review

open access: yesMolecules, 2019
Hypertension is considered a major public health issue due to its high prevalence and subsequent risk of cardiovascular and kidney diseases. Thus, the search for new antihypertensive compounds remains of great interest.
Orsolya Péterfi   +4 more
doaj   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

The effects of endocrine‐disrupting chemicals on ovarian‐ and ovulation‐related fertility outcomes

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 608-631, December 2022., 2022
Abstract Exposure to endocrine‐disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, including the process of ovulation.
Katie L. Land   +3 more
wiley   +1 more source

Enumeration of symmetric centered rhombus tilings of a hexagon [PDF]

open access: yesarXiv, 2013
A rhombus tiling of a hexagon is said to be centered if it contains the central lozenge. We compute the number of vertically symmetric rhombus tilings of a hexagon with side lengths $a, b, a, a, b, a$ which are centered. When $a$ is odd and $b$ is even, this shows that the probability that a random vertically symmetric rhombus tiling of a $a, b, a, a ...
arxiv  

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