Results 101 to 110 of about 22,642,428 (383)
Phospholipase A2 Biochemistry [PDF]
Cardiovascular Drugs and Therapy, 2008 The phospholipase A(2) (PLA(2)) superfamily consists of many different groups of enzymes that catalyze the hydrolysis of the sn-2 ester bond in a variety of different phospholipids. The products of this reaction, a free fatty acid, and lysophospholipid have many different important physiological roles.
Burke, John E, Dennis, Edward A
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Forage Crop Research in the Modern Age
Advanced Science, EarlyView.Forage crops are increasingly vital to sustainable agriculture, yet urgent demands for transformative innovations create unprecedented opportunities and challenges. This review synthesizes the latest advances in forage research, spotlighting cutting‐edge breeding technologies and their transformative potential.
Qikun Liu +11 more
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Proteome and Peptidome of Vipera berus berus Venom
Molecules, 2016 Snake venom is a rich source of peptides and proteins with a wide range of actions. Many of the venom components are currently being tested for their usefulness in the treatment of many diseases ranging from neurological and cardiovascular to cancer.
Aleksandra Bocian +7 more
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Mammalian Phospholipase A2: Phospholipase A2 Receptor
Biological and Pharmaceutical Bulletin, 2004 The phospholipase A2 receptor (PLA2R) is a type I transmembrane glycoprotein related to the C-type animal lectin family such as the mannose receptor. PLA2R regulates a variety of biological responses elicited by secretory phospholipase A2s (sPLA2s). Group IB sPLA2 acts as an endogenous ligand to induce cell proliferation and lipid mediator production ...
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Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion
Advanced Science, EarlyView.This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng +13 more
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Toxins, 2020 Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
Luciana A. Freitas-de-Sousa +14 more
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Harnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance
Drug development research (Print), 2018 The emergence of antibiotic resistance drives an essential race against time to reveal new molecular structures capable of addressing this alarming global health problem.
J. R. Almeida +6 more
semanticscholar +1 more source
Regulation of phospholipase D [PDF]
FEBS Letters, 1999 Structural studies of plant and bacterial members of the phospholipase D (PLD) superfamily are providing information about the role of the conserved HKD domains in the structure of the catalytic center and the catalytic mechanism of mammalian PLD isozymes (PLD1 and PLD2).
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Photometric Determination of Phospholipase A [PDF]
Clinical Chemistry and Laboratory Medicine, 1986 A photometric method for the determination of phospholipase A is described, in which fatty acids are liberated from phosphatidylcholine and measured by a discontinuous enzymatic test. Optimal test conditions were evaluated using purified phospholipase A from human and porcine pancreas.
Hoffmann, G. +3 more
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Advanced Science, EarlyView.Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai +14 more
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