Results 181 to 190 of about 25,150,915 (368)

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

Medicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni, Giulia Galli, Clelia Dallanoce, Marco De Amici, Pau Gorostiza, Carlo Matera   +5 more
wiley   +1 more source

Phospholipase C and phosphatidylinositol phospholipase C.

Clinical Chemistry, 1987
K Hawrylak, R A Stinson
openaire   +3 more sources

Endogenous activity of phospholipases A and C in Ureaplasma urealyticum

Journal of Clinical Microbiology, 1986
N. S. D. Silva, Patricia A. Quinn
semanticscholar   +1 more source

The Properties of Phospholipase Enzymes in Staphylococcal Toxins

, 1965
HAZEL M. DOERY, Björn Magnusson, J. Gulasekharam, Joan E. Pearson   +3 more
openalex   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

Medicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi, Yangzhi Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs   +4 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

Medicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva, Carlo Matera, Silvia Roda, Alessio Colleoni, Marco De Amici, Pau Gorostiza   +5 more
wiley   +1 more source

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

Molecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur, Birsen Yilmaz, Duygu Agagunduz, Yeşim Ozogul   +3 more
wiley   +1 more source

Break down the barriers of auto‐inflammation: How to deal with a monogenic auto‐inflammatory disease and immuno‐haematological features in 2022?

Immunology, Volume 168, Issue 1, Page 1-17, January 2023., 2023
In the past few years, the spectrum of monogenic systemic auto‐inflammatory diseases has widely expanded beyond the typical recurrent fever. Immuno‐haematological features, as cytopenias, hypogammaglobulinemia, hypereosinophilia, lymphoproliferation and immunodeficiency, have been described in association of several MSAID.
Hélène Vergneault, Capucine Picard, Sophie Georgin‐Lavialle   +2 more
wiley   +1 more source

Pomegranate Extracts as Dual Regulators of Angiogenesis: A Systematic Review of Preclinical Evidence in Cancer and Chronic Wound Healing

Molecular Nutrition &Food Research, EarlyView.
Pomegranate extracts contain polyphenols with: anti‐angiogenic properties inhibiting angiogenesis in Cancer resulting in decreased cancer growth; pro‐angiogenic properties promoting angiogenesis in chronic wound healing hence increasing the healing process ABSTRACT Angiogenesis plays a critical role in both tumor progression and wound healing.
Anna Eleonora Caprifico, Gianpiero Calabrese, Riccardo Tornese, Anna Montefusco, Rocco Placì, Teodoro Semeraro, Miriana Durante, Monica De Caroli, Marcello Salvatore Lenucci   +8 more
wiley   +1 more source