Results 221 to 230 of about 25,150,915 (368)

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Bacterial Sphingomyelinases and Phospholipases as Virulence Factors

open access: yesMicrobiology and Molecular Reviews, 2016
M. Flores-Dı́az   +4 more
semanticscholar   +1 more source

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

Virulence profile of pathogenic yeasts from snakes: Alternative ways for antifungal strategies. [PDF]

open access: yesPLoS One
Ugochukwu ICI   +6 more
europepmc   +1 more source

Post-heparin phospholipase and fatty acid transesterification in human plasma

open access: hybrid, 1965
William Vogel   +3 more
openalex   +1 more source

P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho‐GTPase‐dependent motility that requires an interaction with P2Y1 receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy