Metabolic pathways of eicosanoids-derivatives of arachidonic acid and their significance in skin. [PDF]
Biernacki M, Skrzydlewska E.
europepmc +1 more source
Phospholipase C from Bacillus cereus. Evidence for essential lysine residues [PDF]
Bjørg Aurebekk, Christopher B. Little
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Phosphodiesterase 3 inhibitors boost bone outgrowth
Background and Purpose C‐type natriuretic peptide (CNP) stimulates skeletal growth by acting on the growth plates of long bones, and a CNP variant is clinically used for achondroplasia treatment. We previously reported that CNP stimulates the autonomic Ca2+ influx mediated by TRPM7 channels in growth plate chondrocytes to facilitate extracellular ...
Takaaki Kawabe+11 more
wiley +1 more source
Zebrafish sperm outsource activation to eggs' protease-activated receptors. [PDF]
Fissore RA, Lopes EM, Carpentiero F.
europepmc +1 more source
Susceptibility of phospholipids ofProteus mirabilissmooth and rough strains to endogenic phospholipase A activity [PDF]
Shlomo Rottem+3 more
openalex +1 more source
GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng+3 more
wiley +1 more source
Combination of Rhamnetin and RXP03 Mitigates Venom-Induced Toxicity in Murine Models: Preclinical Insights into Dual-Target Antivenom Therapy. [PDF]
Zhao J, Liu G, Shi X, Huang C.
europepmc +1 more source
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito+6 more
wiley +1 more source
Glycerophospholipids: Roles in Cell Trafficking and Associated Inborn Errors. [PDF]
Lamari F, Rossignol F, Mitchell GA.
europepmc +1 more source