Results 251 to 260 of about 22,290,738 (402)

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Molecular Mechanisms Underlying the Pathogenicity of <i>Pseudomonas aeruginosa</i>. [PDF]

Medicina (Kaunas)
Krūmiņa A, Reinis A, Jeske A, Zeltiņa I, Vīksna L.   +4 more
europepmc   +1 more source

Association of Single Nucleotide Polymorphisms in the Prostaglandin-endoperoxide Synthase 2 (PTGS2) and Phospholipase A₂Group IIA (PLA2G2A) Genes with Susceptibility to Esophageal Squamous Cell Carcinoma

, 2014
Fen Liu, Wenqiang Wei, Robert T. Cormier, Shutian Zhang, You‐Lin Qiao, Xin-Qing Li, Sheng-Tao Zhu, Yan-Chun Zhai, Xiao-Xia Peng, Yu-Xiang Yan, Li-Juan Wu, Dian He, Yan He   +12 more
openalex   +2 more sources

Mepacrine, a phospholipase inhibitor

The Journal of Thoracic and Cardiovascular Surgery, 1986
Hajime Otani, Richard M. Engelman, Robert H. Breyer, John A. Rousou, Stanley Lemeshow, Dipak K. Das   +5 more
openaire   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Suppressive effects of bee venom derived phospholipase A2 on mechanical allodynia in a rat model of neuropathic pain

, 2019
Seunghui Woo, Geehoon Chung, Sun Kwang Kim   +2 more
openalex   +1 more source

Fluorometric assay for phospholipase A2 in serum. [PDF]

, 1985
Tom Thurén, Jorma A. Virtanen, M. Lällä, Paavo K.J. Kinnunen   +3 more
openalex   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Genetic Analysis of Virulence and β-Lactamase Determinants Related to β-Lactamase Inhibitors in Pseudomonas aeruginosa Strains from Nosocomial Infections. [PDF]

Antibiotics (Basel)
Paniagua-Contreras GL, Olvera-Navarro E, Herrera-Gabriel JP, González-Vega LV, García-Cortés LR, Moreno-Noguez M, Martínez-Gregorio H, Vaca-Paniagua F, Fernández-Presas AM, Monroy-Pérez E.   +9 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source