Results 251 to 260 of about 25,150,915 (368)

Kinetic analysis of the hydrolysis of lecithin monolayers by phospholipase A [PDF]

, 1971
George Zografi, R. Verger, Gerard H. De Haas   +2 more
openalex   +1 more source

piRNA processing within non‐membrane structures is governed by constituent proteins and their functional motifs

The FEBS Journal, EarlyView.
The silencing of transposable elements is mediated by piRNAs through post‐transcriptional and transcriptional regulation. In Drosophila, piRNAs are processed within unique non‐membrane structures: nuage in germline cells and Yb bodies in somatic gonadal cells.
Ritsuko Suyama, Toshie Kai
wiley   +1 more source

Toxins from Animal Venom-A Rich Source of Active Compounds with High Pharmacological Potential. [PDF]

Toxins (Basel)
Lyukmanova EN, Shenkarev ZO.
europepmc   +1 more source

Phospholipase B activity of a purified phospholipase A from Vipera palestinae venom

, 1973
Joseph Shiloah, Chaya Klibansky, André de Vries, A. Berger   +3 more
openalex   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Molecular Evolution and Adaptation Strategies in Marine Ciliates: An Inspiration for Cold-Adapted Enzyme Engineering and Drug Binding Analysis. [PDF]

Mar Drugs
Pucciarelli S, Mozzicafreddo M, Vassallo A, Piersanti A, Miceli C.   +4 more
europepmc   +1 more source

Fatty‐acid amide hydrolase inhibition mitigates Alzheimer's disease progression in mouse models of amyloidosis

The FEBS Journal, EarlyView.
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Giacomo Giacovazzo, Francesca Ciaramellano, Daniel Tortolani, Alessandro Leuti, Rita Businaro, Federica Armeli, Andras Bilkei‐Gorzo, Roberto Coccurello, Andreas Zimmer, Mauro Maccarrone   +12 more
wiley   +1 more source

Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca: De Novo Assembly and Analysis of Novel Toxic Proteins. [PDF]

Toxins (Basel)
Espín-Angulo J, Vela D.
europepmc   +1 more source

Phosphatidic acid induces cytoskeletal rearrangements through the Src‐FAK‐RhoA/ROCK signaling pathway during decidualization

The FEBS Journal, EarlyView.
Decidualization is the process by which human endometrial stromal cells undergo morphological and functional changes to prepare the uterus for embryo implantation and support pregnancy. Our study identifies the phosphatidic acid‐Src‐FAK‐RhoA/ROCK signaling pathway as a critical regulator of the cytoskeletal alterations required for this transformation.
Hyeon‐Jeong Jun, So Young Lee, Shin‐Young Park, Joong Sub Choi, Mee‐Sup Yoon, Joong‐Soo Han   +5 more
wiley   +1 more source

Editorial: Direct modulation of ion channels by G-proteins. [PDF]

Front Physiol
Yakubovich D.
europepmc   +1 more source